OBJECTIVES To compare the effectiveness of in vitro fertilisation with single embryo transfer or in vitro fertilisation in a modified natural cycle with that of intrauterine insemination with controlled ovarian hyperstimulation in terms of a healthy child. DESIGN Multicentre, open label, three arm, parallel group, randomised controlled non-inferiority trial. SETTING 17 centres in the Nether...

Background: The success of therapeutic results of assisted reproductive techniques is related to several factors, including the extent of female anxiety. The aim of this study was to determine the effect of training problem solving skills on the anxiety of female candidates for intrauterine insemination in Moheb Yas Hospital in Tehran (2015). Methods: This experimental study was a two-group de...

For many years, the management of male-factor infertility has been empirical rather than evidence-based. In current clinical practice, assisted reproductive techniques are the most successful methods of alleviating male-factor infertility. To date, it remains unclear what adjuvant actions can be taken to improve the outcome of assisted reproductive techniques for male-factor infertility. Eviden...

Anti-Müllerian Hormone (AMH) is a member of the transforming Growth Factor-B (TGF-B) family synthesized exclusively by the gonads of both sexes. Over the last four years, numerous studies have examined the clinical usefulness of serum AMH levels as a predictor of ovarian response and pregnancy in assisted reproductive technology cycles. Assessment of ovarian reserve in women undergoing assisted...

BACKGROUND Many women throughout the world have history of subfertility (resolved or unresolved), but much remains unknown about services and treatments chosen. METHODS We developed a mixed-mode fertility experiences questionnaire (FEQ) in 2009 through literature review and iterative pilot work to optimize question format and mode of administration. The focus of the FEQ is to collect data ret...

The uterus plays a major role in sperm migration, embryo implantation, and fetal development. Congenital uterine anomalies and acquired uterine lesions may affect such uterine functions precluding successful pregnancy. Despite advances in the field of assisted reproductive techniques (ART), only one-third of cycles started end in a pregnancy and one-fourth result in a live birth [1]. Intrauteri...

INTRODUCTION Fertility is referred to the capability for having offspring and can be evaluated by fertility rate. Women's fertility is strictly dependent on individual's age. The fertility peak occurs in the early 20s, and it starts to decline in the third and fourth decades of life (falling sharply after age 35). AIM The aim of this work is to review the available data concerning fertility i...

BACKGROUND Although heterotopic gestation is common in assisted reproductive techniques, it is very rare in natural conception and clomiphene induced pregnancy. Diagnosis and appropriate intervention of heterotopic pregnancy requires a high index of suspicious. CASE In this paper a case of heterotopic pregnancy in a 30-year old woman with hemoperitoneum from ruptured tubal pregnancy with live...