Beckwith-Wiedemann Syndrome is a congenital disease associated with macrosomia, macroglossia, abdomianl wall defects, hemihypertrophy, neonatal hypoglicemia, microcephaly and musculoskeletal system abnormalities. The aim of this case report is to present our anesthesia experience in a 10 year old patient with BeckwithWiedemann syndrome in whom could not be intubated with external laryngeal mani...

1. McAllister KG: Macroglossia: A positional complication. ANEsrlrrSIOI.OGY 1974; 40: 199 -200 2. Ellis SC, Bryan-Brown CW, Hyderally H: Massive swelling of the head and neck. AHESIHESIOLOGY 1975; 42:102-3 3. Teeple E, Maroon J, Rueger J: Hemimacroglossia and unilateral necrosis of the tongue in a king-duration neurosurgical procedure. ANESTHESIOI.O(;Y 1986; 64:8456 4. Mayhew JF, Miner M, Katz ...

The syndrome of exomphalos, macroglossia, postnatal somatic gigantism and severe hypoglycaemia in various combinations was first described in seven infants by Beckwith (1963) and Beckwith et al. (1964). At necropsy the main features were cytomegaly of the foetal adrenal cortex, renal medullary dysplasia, and hyperplasia of the pancreas and kidneys. Wiedemann (1964) reported three siblings of a ...

Vascular or lymphatic malformation can present as a diffuse tongue mass, suggested by a bluish hue or overlying vesicles. Tuberculosis, hypothyroidism, acromegaly, and idiopathic muscular hypertrophy manifest clinically as macroglossia, for which the diagnosis is aided by the medical history and other physical signs. Moreover, the nodular appearance of the macroglossia suggests other pathologie...

Sir, Multiple myeloma is a monoclonal B-cell neoplasm, which is characterized by autonomous proliferation of immunoglobulin-secreting plasma cells, capable of synthesizing amyloidogenic light chains (AL). AL amyloidosis is characterized by extracellular deposition of eosinophilic, homogeneous, amorphous material composed of fibrillary protein, containing light chain fragments (1). The oral clin...

A 69-year-old man had dyspnea followed by slowly progressive proximal leg weakness over 2 years. He had macroglossia (figure 1). Creatine kinase was 1,378 U/L. A deltoid biopsy revealed myopathy, denervation atrophy, and congophilic deposits around perimysial vessels, indicating amyloid (figure 2). Further workup revealed serum monoclonal lambda protein, bone marrow amyloid, and cardiomyopathy....