Podocyte damage plays a central role in the pathogenesis of idiopathic nephrotic syndrome, as well progression many chronic glomerular diseases. Targeted therapy these diseases still represents challenge. We have previously shown that c-mip (c-maf inducing protein) pivotal podocyte minimal change syndrome patients. In this context, we implement non-viral approach targeting expression podocytes ...

We present here the recent developments in the studies of self-organization in abiotic, biotic (bacterial) colonies and man-made (programmable chips) systems, aimed at seeking to unravel the general principles of biotic self-organization. A typical bacterial colony consists of 10 − 10 bacteria. It is not created by pre-design or according to a plan, but through a process of biotic self-organiza...

In this paper, we point to the potential and implications of digital traces as novel data source in the study of contemporary activities and behaviors. We do this to raise awareness of IS researchers of such traces in increasingly complex sociomaterial practices. We develop a two-dimensional framework of data sources (subjective/objective and digitalized/non-digitalized) for analyzing a six-yea...

The objective of this paper is to investigate the feasibility of making structural systems from ceramics. Segmental and composite systems are quantitatively studied, partial application of ceramics to traditional systems is considered, and the special application of a lunar base is studied. The quantitative and qualitative studies made indicate both advantages and disadvantages for ceramics in ...