We compared overexpression of the magnetotactic bacterial gene MagA with the modified mammalian ferritin genes HF + LF, in which both heavy and light subunits lack iron response elements. Whereas both expression systems have been proposed for use in non-invasive, magnetic resonance (MR) reporter gene expression, limited information is available regarding their relative potential for providing g...

PURPOSE Endogenous endophthalmitis secondary to Klebsiella pneumoniae liver abscess is a blinding infection that is being reported more frequently in the literature. The K1 capsule and magA contribute to virulence of systemic infection in mice; however, little is known about the role of magA in secondary ocular infections. METHODS To assess the role of K. pneumoniae capsule in endophthalmitis...

UNLABELLED Finasteride 1 mg, one of the main treatments for male androgenetic alopecia (MAGA), may produce sexual dysfunction, but young men with MAGA could experience high psychosocial impairment because of changes in body image. Dissatisfaction with body image has been linked to an increase in problems with sexual function. To date no study has considered the possible effect of psychological ...

BACKGROUND AND OBJECTIVES Klebsiella pneumoniae (K. pneumoniae) is an opportunistic microorganism. This study aimed to investigate the presence of magA gene and antimicrobial susceptibility in K. pneumoniae. MATERIALS AND METHODS clinical specimens were collected from hospitals of Shahrekord, Iran. Bacterial culture, biochemical diagnostic standard test, determination of antibiotic sensitivit...

Foi estudado a complexação do ácido guanidoacético (AGA) com alguns íons de interesse biológico, a saber : Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) e Pb(II). Após o AGA ter sido sintetizado e caracterizado, foram determinadas potenciometricamente as constantes de dissociação deste ligante, assim como a de formação de seus complexos e hidroxicomplexos com os íons supracitados. A maioria do...

BACKGROUND Klebsiella pneumoniae has been the dominant pathogen for liver abscesses in several Asian countries. Although the prevalence of K. pneumoniae liver abscess (KLA) in mainland China is increasing recently, the clinical and microbiological characteristics of KLA in China have not been elucidated. METHODS Clinical and microbiology characteristics of 45 consecutive patients with KLA fro...

BACKGROUND AND PURPOSE Klebsiella pneumoniae causes a wide spectrum of infections, including abscess and non-abscess formation. This study investigated the clinical spectrum and molecular characteristics of community-acquired Klebsiella infection with primary extrahepatic abscess. METHODS From April 2004 through March 2007, a total of 18 strains of K. pneumoniae, 11 from blood and 7 from foca...

We report the emergence of five carbapenem-resistant K1 hypervirulent Klebsiella pneumoniae (hvKP) strains which caused fatal infections in hospital patients in Zhejiang Province, China, upon entry through surgical wounds. Genotyping results revealed the existence of three genetically related strains which exhibited a new sequence type, ST1797, and revealed that all strains harbored the magA an...

.............................................................................................................................. ii Acknowledgments .............................................................................................................. iii Table of Contents ............................................................................................................... iv Lis...