nano-sized drugs have better distribution than their identical forms. magnesium is the cofactor of various enzymes in lipid and glucose metabolism. in this study the effect of nano-magnesium oxide (nano-mgo) on glucose concentration and lipid profile in diabetes induced mice was evaluated in 21 laboratory mice. mice were divided randomly into three equal groups (control, treatment and placebo)....

The following sentence in the abstract ‘Certain individuals will need to supplement with magnesium in order to prevent suboptimal magnesium deficiency, especially if trying to obtain an optimal magnesium status to prevent chronic disease.’ should be: ‘Certain individuals will need to supplement with magnesium in order to prevent subclinical magnesium deficiency, especially if trying to obtain a...

OBJECTIVE To review the function and use of intravenous magnesium in magnesium depleted and non-magnesium depleted patients. DATA SOURCES A review of studies reported from 1966 to 1998 and identified through a MEDLINE search of the English-language literature on the use of intravenous magnesium. SUMMARY OF REVIEW Magnesium is a metalo-coenzyme that participates in numerous enzymatic reactio...

Magnesium is involved in numerous processes that affect muscle function including oxygen uptake, energy production and electrolyte balance. Thus, the relationship between magnesium status and exercise has received significant research attention. This research has shown that exercise induces a redistribution of magnesium in the body to accommodate metabolic needs. There is evidence that marginal...

Hypomagnesemia is defined as a serum magnesium level less than 1.8 mg/dL (< 0.74 mmol/L). Hypomagnesemia may result from inadequate magnesium intake, increased gastrointestinal or renal losses, or redistribution from extracellular to intracellular space. Increased renal magnesium loss can result from genetic or acquired renal disorders. Most patients with hypomagnesemia are asymptomatic and sym...

Data from nationwide population-based nutrition surveys in Taiwan were used to investigate trends and nutritional status for magnesium from 1993 to 2008. Dietary magnesium intake was estimated from 24-hour dietary recalls. Serum and urinary magnesium were also measured. In Nutrition and Health Survey in Taiwan (NAHSIT) 2005-2008, average magnesium intake was 305 mg and 259 mg for adult males an...

In type 2 diabetes mellitus (T2D), the handling of magnesium is disturbed. Magnesium deficiency may be associated with a higher risk of coronary heart disease (CHD). We investigated the associations between (1) dietary magnesium intake; (2) 24 h urinary magnesium excretion; and (3) plasma magnesium concentration with prevalent CHD in T2D patients. This cross-sectional analysis was performed on ...

BACKGROUND Atrial fibrillation (AF) is the most common cardiac arrhythmia. Magnesium has been reported to be effective in reducing the incidence or prophylaxis of AF. Magnesium is also an essential constituent of many enzyme systems and plays a physiological role in coagulation regulation. The aim of the present study was to examine the effects of magnesium, whether magnesium infusion might dec...

In this study, fertilized mirror carp eggs were allowed to develop in fresh water with various magnesium concentrations (0.05, 0.2 and 2 mg l). The percentage of dead (eggs+prelarvae) and deformed prelarvae increased sharply to 94% at an ambient magnesium concentration of 0.05 mg l compared with 22 and 10% at ambient magnesium concentrations of 0.2 mg l and 2.0 mg l, respectively. Mirror carp r...

Despite its success as a potent antineoplastic agent, ∼25% of patients receiving cisplatin experience acute kidney injury (AKI) and must discontinue therapy. Impaired magnesium homeostasis has been linked to cisplatin-mediated AKI, and because magnesium deficiency is widespread, we examined the effect of magnesium deficiency and replacement on cisplatin-induced AKI in physiologically relevant o...