melanoma of the oral cavity is a rare malignant disease. on account of the presence at relatively obscure areas in the oral cavity, most of oral malignant melanomas are diagnosed at a late stage. early diagnosis is essential for successful treatment and perhaps is the key factor in improving the prognosis of oral malignant melanoma. however, no large clinical series exist, and in fact, clinical...

background: malignant melanoma, one of the most deadly skin cancers, is a skin tumor that arises from the epidermal melanocytes. the aim of this study is to evaluate the demographic and clinical data of malignant melanoma patients in a referral dermatology center in the south of iran. methods: in this retrospective study, we have reviewed files of 116 patients diagnosed with malignant melanoma ...

in order to distinguish between benign and malignant types of pigmented skin lesions, computerized procedures have been developed for images taken by different equipment that the most available one of them is conventional digital cameras. in this research, a new procedure to detect malignant melanoma from benign pigmented lesions using macroscopic images is presented. the images are taken by co...

malignant melanoma is a potentially aggressive tumor of melanocytic origin. primary oral malignant melanoma is a rare neoplasm, accounting for 0.5% of all oral malignancies. the present case occurred in a 60‑year‑old female patient, as a pedunculated growth involving the palate and alveolar ridge and histologically showing a desmoplastic differentiation. the article discusses the distinct clini...

a 75-year–old patient was referred with vaginal bleeding. her physical exam showed two flat dark plaques on the posterior fourchette, mostly on left lateral side of the vulva. a black soft mucosal nodule was present on the left lateral side of upper vagina, and a polypoid ulcerative cervical lesion extended into the right parametrium. cervical and vaginal biopsies were in favor of malignant mel...

abstract: objective: giant cell tumor of soft parts is a rare neoplasm that mainly affects adulst and the elderly and is usually located in the extremities. here we report a child with giant cell tumor of soft tissue, which is a very rare condition in childhood. clinical presentation: a 5 year old girl presented with a 5 month history of left lower extremity pain. she had developed paraplegia b...

Although gastrointestinal involvement by metastatic malignant melanoma is common but primary gastrointestinal (GI) melanoma has been reported in rare cases. In this study we report two cases of primary gastrointestinal malignant melanoma that one of them is a known case of neurofibromatosis type 1(NF1). Both cases showed no evidence of any lesions in skin and eye. Malignant melanoma of GI tract...

zosteriform metastasis is a rare clinical distribution from spreading neoplasms of every organ to the skin. tumors most often arise from a n internal o r hematologic malignancy. w e report a 69-year-old man, a known case of malignant melanoma of the left heel. in this case, multiple red-brown metastatic nodules appeared four months after diagnosis. distribution of metastatic lesions resembled a...

introduction primary malignant esophageal melanoma makes up 0.1% to 0.2% of all esophageal malignancies. most physicians assume malignant melanoma as a skin originated neoplasm, however this type of melanoma can occur anywhere in the gastrointestinal tract especially in the esophagus. thus, it is essential to consider malignant melanoma in differential diagnosis of any esophagus masses. case pr...

Introduction: cyclooxygenase-2 (COX-2) is involved in pathogenesis of various tumors and possibly malignant skin tumors including malignant melanoma; however, there is not enough information about COX-2 expression in benign melanocytic lesions. In the present study we compared the expression levels of COX-2 in malignant melanoma and benign melanocytic lesions. Method: In this analytical study, ...