keywords: Unstable angina, Glutathione, Malonyldialdehyde ABSTRACT Introduction: There is now a consensus that atherosclerosis represents a state of heightened oxidative stress which is characterized by lipid and protein oxidation in the vascular wall. Inspite of many efforts which were made to explain the role of oxidative stress in progression of CAD (Coronary Artery Disease), its predictive ...

Background: Plant oxysterols like 28-homobrassinolide (HB) exhibit partial structural homology to oxycholesterols. HB’s effect in cell metabolism was therefore investigated using rat model. Results: Oral administration of HB to streptozotocin induced diabetic male albino wistar rats, reduced circulating glucose level to normal level. Serum insulin content was increased by HB treatment. HB eleva...

The aim of this work was to evaluate the possibility of using of the new selenoorganic ring compound, 3-(o-chlorobenzoylamino)-2-(o-tolylimino)-4-methyl-4-selenazoline, as a selenium supplement by investigating the influence of its short-term administration on Se accumulation and antioxidant status in kidney. For 10 days, adolescent male Wistar rats were treated with saline (control group), Na(...

Twenty patients with definite or classical rheumatoid arthritis entered and completed a sequential study of placebo for 1 week, oral indomethacin 25 mg 3 times a day for 3 weeks, and oral indomethacin 25 mg 3 times a day plus 100 mg indomethacin suppository at night for 3 weeks. Twelve of the patients had previously been classified as responders and eight as nonresponders to indomethacin by an ...

The purpose of the experiment was to check the prevention from ongoing lipid peroxidation by 4-hydroxytempo (Tempol) treatment in the burned rat. The burn disease rat model was used for the estimation of Tempol ability to scavenge increased amounts of free radicals and prevent spreading of lipid peroxidation process. Four groups of male Wistar rats were used in the experiment. Saline or Tempol ...

Objective Human serum paraoxonase (PON1) prevents lipids from peroxidation and functions as an antioxidant mechanism. Malonyldialdehyde (MDA) is the final product of lipid peroxidation and can be used as an indicator of oxidative stress. The aim of this study was to investigate PON1, MDA, and arylesterase (ARY) levels in schizophrenic patients who are taking typical, atypical, or combined (typi...

Dechlorane Plus (DP) and Tetrabromobisphenol A (TBBPA) are the halogenated flame retardant with highest production volume, cadmium (Cd) is regarded as one of hazardous heavy metals due to its bio toxicity bioaccumulation in environment, it will cause environmental pollution affect human health, so a pot experiment was conducted investigate phytotoxicity on seed germination seedling two rice var...

A new melted bioactive system containing gold nanoparticles (AuNPs) was prepared exploiting a post-synthesis thermal treatment that allows one to modify crystal phases and nature, shape and distribution of the gold species in the glass-ceramic matrix as evidenced by UV-visible spectroscopy, transmission electron microscopy and powder X-ray diffraction analysis. In human MG-63 osteoblasts the pr...

The aim of the present study is to evaluate of the impact of immunonutrition on parameters of oxidative stress and inflammation in patients with cystic fibrosis and malnutrition. In the 30 patients with cystic fibrosis and long-term enteral nutrition support for malnutrition the effect of standard and immunonutrion sipping on oxidative stress and inflammatory activity parameters was compared. M...