While the importance of random sequencing errors decreases at higher DNA or RNA sequencing depths, systematic sequencing errors (SSEs) dominate at high sequencing depths and can be difficult to distinguish from biological variants. These SSEs can cause base quality scores to underestimate the probability of error at certain genomic positions, resulting in false positive variant calls, particula...

UNLABELLED Salivary gland side effects (SSEs) can be a source of significant morbidity in thyroid cancer patients receiving radioactive iodine (RAI) for remnant ablation or therapy. However, the incidence, time course, and ultimate resolution of SSEs that develop in the first few months after a single administered activity of RAI for remnant ablation has not be adequately defined. METHODS We ...

Secondary-structure elements (SSEs) play an important role in the folding of proteins. Identification of SSEs in proteins is a common problem in structural biology. A new method, ASSP (Assignment of Secondary Structure in Proteins), using only the path traversed by the C(α) atoms has been developed. The algorithm is based on the premise that the protein structure can be divided into continuous ...

Objective: This study is an attempt to investigate validity and reliability of the Persian version of Sexual Self-Efficacy Scale-Female functioning in volunteer married women in married dormitories and non-dormitories of Shahid Beheshti University of Tehran, Iran. Methods: The current study is descriptive of type survey. The sample consisted of 160 volunteer married women in mar...

OBJECTIVE Bulimia nervosa (BN) is associated with low self-esteem. This study was designed to assess whether low self-esteem persists in nondepressed individuals who have recovered from BN (BN-R). METHOD Study groups included BN (n = 22), BN-R (n = 20), and healthy controls (n = 42). Participants were medication-free, and none met criteria for current major depression. Assessment instruments ...

Korea needs national strategies to handle problems of Small Scale Enterprises (SSEs) systematically. Since 1993, the Korean government has begun to provide financial subsidy programs for Occupational Health Services (OHSs) in SSEs from Occupational Injury Prevention Fund. To identify the health care status in SSEs in Korea, 5,080 factories, which had participated in the Government-funded Subsid...

EM-Fold was used to build models for nine proteins in the maps of GroEL (7.7 Å resolution) and ribosome (6.4 Å resolution) in the ab initio modeling category of the 2010 cryo-electron microscopy modeling challenge. EM-Fold assembles predicted secondary structure elements (SSEs) into regions of the density map that were identified to correspond to either α-helices or β-strands. The assembly uses...

With the ability to observe the activity from large numbers of neurons simultaneously using modern recording technologies, the chance to identify sub-networks involved in coordinated processing increases. Sequences of synchronous spike events (SSEs) constitute one type of such coordinated spiking that propagates activity in a temporally precise manner. The synfire chain was proposed as one pote...

[1] A large slow slip event (SSE) had been expected for the Guerrero gap for 2010. It was actually observed with an onset in July 2009. Comparison with the preceding large SSEs, which occurred in 2002 and 2006, highlights both persistent characteristics of the Guerrero SSEs (e.g. the localization of slip in the seismogenic part of the subduction interface), and also particularities of the 2009/...

BACKGROUND Real-world treatment patterns of bone metastatic castration-resistant prostate cancer (mCRPC) in Japan were examined, focusing on treatment patterns and resource use differences attributed to symptomatic skeletal events (SSEs). METHODS Urologists (N = 176) provided retrospective chart data for patients with mCRPC (N = 445) via online surveys. Descriptive analyses and chi-square tes...