purpose : to compare the cosmetic and functional results of frontalis sling procedure using silicone rod with polytetrafluoroethylene (ptose-up) in congenital ptosis with poor levator function (lf) methods : in a prospective randomized study, 90 eyes of 66 patients with congenital ptosis that underwent frontalis suspension surgery [31 patients (18 unilateral, 13 bilateral cases) using a silicon...

To analyse the effect of congenital unilateral ptosis on the ocular higher order aberrations (HOA) and to compare these eyes with normal fellow eyes this study has been performed. In this observational comparative case series, 16 eyes of 16 patients less than 15 years old with congenital unilateral upper eyelid ptosis were included. Corrected distance visual acuity (CDVA), corneal topography, o...

PURPOSE To evaluate the safety and efficacy of injecting hyaluronic acid gel in the upper eyelid as a nonsurgical alternative in the treatment of paralytic lagophthalmos. METHODS This is a retrospective study of 9 patients (10 eyelids) with paralytic lagophthalmos treated with hyaluronic acid gel in the prelevator aponeurosis region and/or pretarsal region of the paralytic upper eyelid. Pretr...

PURPOSE To evaluate the outcome of eyelid retraction surgery in thyroid-related orbitopathy (TRO) patients in 2 different surgical settings: done simultaneously with orbital decompression or as a staged procedure after orbital decompression. DESIGN Retrospective, comparative, nonrandomized clinical study. PARTICIPANTS Ninety-six patients (158 eyes). METHODS A review of electronic medical ...

PURPOSE To evaluate of functional and cosmetic effectiveness of lower eyelid sling technique with fascia lata graft in patients with lagophthalmos due to facial paralysis. MATERIAL AND METHOD Ten patients with a mean age of 55.1 ± 19.77 years who underwent lower eyelid sling surgery with a fascia lata graft between September 2011 and January 2014 were included in this prospective study. Preop...

Ribosome biogenesis in eukaryotes requires coordinated folding and assembly of a pre-rRNA into sequential pre-rRNA-protein complexes in which chemical modifications and RNA cleavages occur. These processes require many small nucleolar RNAs (snoRNAs) and proteins. Rbm19/Mrd1 is one such protein that is built from multiple RNA-binding domains (RBDs). We find that Rbm19/Mrd1 with five RBDs is pres...

purpose: to assess the etiology, demography, surgical management and postoperative complications of ptosis in a referral ophthalmologic center. methods: we reviewed records of 233 ptosis patients managed at labbafinejad hospital during 1998-2003. etiology, age, sex, laterality, family history, amblyopia, past medical history, margin reflex distance and levator function, type of surgery, and pos...

Ribosomal subunit biogenesis in eukaryotes is a complex multistep process. Mrd1 is an essential and conserved small (40S) ribosomal subunit synthesis factor that is required for early cleavages in the 35S pre-ribosomal RNA (rRNA). Yeast Mrd1 contains five RNA-binding domains (RBDs), all of which are necessary for optimal function of the protein. Proteomic data showed that Mrd1 is part of the ea...

PURPOSE To compare morphometric data of eyelid fissure using computerized image analysis before and after application of botulinum toxin type A in patients with eyelid retraction caused by dysthyroid orbitopathy in acute stage. METHODS This was a prospective study with 12 individuals that received transcutaneous 5 UI/0.1 ml injection of botulinum toxin in the upper eyelid. They were examined ...