Background: Stroke is a leading cause of death all around the world, and ischemic stroke is considered to be the most common stroke type. Toll-like receptors (TLRs) are important molecules for detection of both pathogen invasion and tissue damage. In this regard, the purpose of this study was to assess the expression level of TLR2 on monocytes in patients with ischemic stroke and to evaluate th...

numerous etiologies are responsible for cases of stroke in young adults. this study reviews the causes of two types of stroke (ischemic and intracerebral hemorrhage) in young adults aged 15 to 40years, admitted to our center (a tertiary care center) from 1997 to 2002. the purpose of this study is to determine the relative frequency of causes of stroke in young adults and compare this with publi...

background: epidemiological research has shown that increased total homocysteine (thcy) levels are associated with an increased risk of thromboembolic disease; however, controversy still exists over which subtype of stroke is allied to hyperhomocysteinemia. this study aimed to investigate whether elevated thcy is an independent risk factor for ischemic stroke and to compare thcy levels in patie...

background:  intravenous  recombinant  tissue plasminogen  activator  (rt-pa) is an approved  treatment for acute ischemic stroke within 4.5 h of symptoms onset. decompressive craniectomy (dc) has been  shown  as an effective  therapeutic  modality in malignant  middle cerebral  artery (mca) infarction. as rt-pa could result in hemorrhagic  complication during or after any surgery dc may be ass...

background: although the risk factors of ischemic strokes are well defined, there is slight information about their relations with the etiologies of ischemic strokes. this study investigated the distribution of ischemic stroke risk factors and their connections to diverse etiologies of cerebrovascular attack (cva) and specific ischemic regions of brain. methods: in this cross sectional study , ...

objective: the results of the previous studies on the correlation between plasma levels of homocysteine (hcy) and ischemic stroke have been controversial. the aim of the present study is to investigate this correlation meticulously observing risk factors for the ischemic stroke as well as factors affecting the plasma levels of hcy. method: a case-control study was conducted between 2005-2006 wi...

A very simple and low-cost brain dedicated, rapidly rotating Single Photon Emission Tomograph SPECT is described. Its use in following patients with ischemic stroke is illustrated by two middle cerebral artery occlusion cases, one with persistent occlusion and low CBF in MCA territory, and one with early lysis of the occlusion having high CBF (massive luxury perfusion) for some weeks. Evidence ...

introduction: the therapeutic potential of anandamide (aea) for the neurological disorders may be negatively affected by its short half-life or poor solubility. the superior properties of carbon nanotubes (cnts) for controlled drug delivery, prompted us to design aea-cnts complex and assess its effect in in vitro model of ischemic stroke. methods: in this experimental study, a multi-walled cnts...

BACKGROUND Little is known about the incidence and risk factors of early consciousness disorder (ECD) in patients with acute ischemic stroke, or about how ECD may affect complications and outcomes. METHODS Patients admitted to our hospital within 24 h of onset of acute ischemic stroke were consecutively enrolled. ECD was evaluated clinically and using the Glasgow coma scale. Multivariate anal...