than 40 or less than -40 was defined as left or right hemisphere language dominancy, respectively. Otherwise, language dominancy was not determined (ambiguous). The relationship between the side of epileptogenic focus and language-dominant hemisphere was investigated.Results: Language dominancy was identified in the left hemisphere in 75% (9/12) of the cases with right hemisphere epilepsy, in 5...

Estroprogestins (EPs) are combinations of estrogen and progestin with several actions on women's health. The different pharmacological composition of EPs is responsible for different clinical effects. One of the most used low-dose EP associations is ethinylestradiol 20 mcg plus levonorgestrel 100 mcg in monophasic regimen (EE20/LNG100). This review summarizes clinical pharmacology, cycle contro...

Enteric fever is prevalent in developing countries including Nepal, where it still remains as a major health problem. Appropriate antibiotics are essential for the treatment of typhoid and paratyphoid fever. A prospective study was carried out to characterize the epidemiological features of enteric fever in Kathmandu, Nepal and to analyse the recent trend of antimicrobial resistance pattern of ...

Aim: The present study investigated the inhibitory effect of methanolic extract of Couroupita guianensis leaves (MCG) on carbohydrate hydrolysing enzymes and glucose uptake in isolated rat hemidiaphragm. Method: The effects of MCG at different concentrations (1.25-10mg) were carried out on carbohydrate hydrolysing enzymes namely porcine pancreatic αamylase, rat intestinal α-glucosidase and sucr...

We study the large scale geometry of mapping class groups MCG(S), using hyperbolicity properties of curve complexes. We show that any self quasi-isometry of MCG(S) (outside a few sporadic cases) is a bounded distance away from a left-multiplication, and as a consequence obtain quasi-isometric rigidity for MCG(S), namely that groups quasi-isometric to MCG(S) are virtually equal to it. (The latte...

OBJECTIVES To evaluate basal plasma cortisol in persistent asthmatics on inhaled fluticasone propionate 200 mcg/day and 300 mcg/day. METHODS Asthma diagnosis and classification was based on Global Initiative for Asthma recommendations. Patients aged 11 years old or less received fluticasone propionate 200 mcg/day and those older than 11 years received 300 mcg/day. After 10 weeks of treatment,...

BACKGROUND The EVIDENCE (EVidence of Interferon Dose-response: European North American Comparative Efficacy) study was an international, randomized, open-label, assessor-blinded, parallel-group study assessing the efficacy and tolerability of interferon (IFN) beta-1a, 44 mcg subcutaneously (sc) three times weekly (tiw), and IFN beta-1a, 30 mcg intramuscularly (im) once weekly (qw), in patients ...

BACKGROUND Cyclosporine A (CsA) is used as a posttransplantation immunosuppressant drug, and careful monitoring of CsA concentration in whole blood is essential. A new automated electrochemiluminescence immunoassay (ECLIA) for CsA measurement has been assessed in a multicenter evaluation. METHODS Residual EDTA whole blood samples from patients undergoing CsA therapy after organ transplant wer...

BACKGROUND/AIM Medicamentous abortion was first introduced in Serbia and Montenegro in September 2001. The aim of this study was to assess the efficiency, side effects, and acceptability of medicamentous abortion using mifeprostone orally (600 mg), and 48 hours later, misoprostol both orally and vaginally in different regiments in our population (400 mcg, 600 mcg, 800 mcg). METHODS A total of...

Introduction: Uropathogenic Escherichia coli (UPEC) is among the primary cause of urinary tract infections (UTIs). This study was conducted to determine the antibiotic resistance pattern of E. coli isolates from UTIs in Kermanshah. Methods: In this study, 180 midstream urine samples were collected from outpatients for five months. Based on differential biochemical tests such as oxidase, Indole,...