there is no randomized study carried out in order to compare their pharmacokinetic parameters although midazolam, as a sedative, has been widely administered via continuous infusion as well as intermittent bolus doses in mechanically ventilated critically ill patients. we prospectively investigated the effect of these two principal methods on pharmacokinetic parameters in 23 of mentioned patien...

objectives the aim of this study was to study the incremental cost-effectiveness ratio associated with the use of heat and moisture exchangers (hme) filter to prevent vap compared with the heated humidifiers (hh) presently adopted by intensive care unit (icu) services within the brazilian healthcare unified system. patients and methods this study was a cost-effectiveness analysis (cea) comparin...

Background Many neonates admitted to Neonatal Intensive Care Unit (NICU) need mechanical ventilation for recovery. This study was designed to evaluate the short-term outcome of mechanically ventilated neonates admitted to NICU. <span style="fon...

background : since the use of high concentrations of oxygen in infants may lead to chronic lung problems, using proper methods of care in infants under mechanical ventilation is one of the most important measures in nicu. this study aimed to investigate the effects of prone and supine positions on oxygenation (spo 2 ) in premature infants under mechanical ventilation and comparing infants’ oxyg...

background: application noninvasive ventilation in the patients with exacerbation of chronic obstructive pulmonary disease (copd) reduced mortality. this case-control study was designed to compare efficiency and outcome of non-invasive (niv) versus invasive positive pressure ventilation (ippv) in respiratory failure due to copd methods: the patients were assigned to niv or ippv intermittantly.t...

background endotracheal suctioning is a necessary procedure practiced by nurses in intensive care units to remove lung secretions. this procedure leads to higher oxygenation levels and reduced breathing difficulties. it also prevents atelectasis, pulmonary infections, and the accumulation of secretions. objectives the present study aims to compare the effectiveness of open and closed endotrache...

Background: Respiratory distress syndrome (RDS) is a medical emergency in infants resulting from a lack of or deficiency in surfactant, and leads to pulmonary failure. Surfactant and mechanical ventilation are among the primary treatments for helping infants with respiration. Some sedative drugs, such as benzodiazepines and opioids, are used to reduce stress and restlessness in...