Meconium aspiration syndrome is a cause of significant morbidity and mortality in the perinatal period and has been implicated in the pathogenesis of airway dysfunction. In this study, we developed a murine model to evaluate the effects of meconium aspiration on airway physiology and lung cellular responses. Under light anesthesia, BALB/c mice received a single intratracheal instillation of mec...

Table II in the article shows thin meconium in trachea in 51.9% of the cases, whereas Table III shows thin meconium in trachea in 54.8% of the cases! Table IV shows that out of 9 babies who had intrapartum suctioning alone only one baby developed Meconium Aspiration Syndrome (MAS) (11.1%), while of those who received both intrapartum suctioning and endotracheal suctioning, 16.1% developed MAS t...

BACKGROUND Despite the common occurrence of intrauterine meconium passage and resultant meconium aspiration syndrome (MAS), controversies regarding the pathophysiology and use of appropriate preventive strategies abound. METHODS Databases from MEDLINE, MD Consult, and the Science Citation Index were searched from 1964 to the present to find relevant sources of information. RESULTS AND CONCL...

Purpose: This study was undertaken to assess the relationship between the degree of meconium staining of the extraplacental membranes at birth, meconium aspiration, and pulmonary changes in neonates and stillbirth. Methods: The lungs, extraplacental membranes and placenta from 20 stillborn with meconium-stained membranes and 13 lungs of perinatal deaths were collected and microscopically examin...