OBJECTIVE To determine if amnioinfusion with an antibiotic solution decreased the rate of clinical chorioamnionitis and puerperal endometritis in patients with meconium-stained amniotic fluid. METHODS Patients in labor at 36 weeks of gestation or greater with singleton pregnancies and meconium-stained amniotic fluid were randomized to receive either cefazolin, 1 g/1,000 mL, of normal saline (...

During the second and third trimesters increasing activities of the glycolytic enzyme pyruvate kinase are to be found in human amniotic fluid. At term (37 to 42 weeks), a very steep rise in amniotic fluid pyruvate kinase can be noticed, which may serve as an additional prenatal indicator of fetal maturity. The presumable main sources of the enzyme in amniotic fluid are the epithelium cells of t...

Although the pathway for fetal defecation exists, this does not usually occur. In most cases the first defecation occurs postnatally; the bile-stained fecal matter is called meconium. In 10 15% of all deliveries, the neonate's amniotic fluid is meconium-stained, indicating some amount of in utero defecation. Even though about one-third of such neonates will have some meconium in their lungs, on...

Background: The significance of meconium in amniotic fluid is a widely debated subject. Traditionally meconium has been viewed as a harbinger of impending or ongoing fetal compromise; however some investigators believe that it is not associated with fetal hypoxia, acidosis or fetal distress. Others have found lower Apgar scores in meconium stained neonates. Objectives: To study the correlation ...

Keywords: Meconium stained amniotic fluid (MSAF) Pregnancy outcome Clear amniotic fluid (CAF) Original Article Objectives: To identify risk factors for meconium stained amniotic fluid (MSAF) and comparison of pregnancy outcome in meconium stained vs. clear amniotic fluid. Methods: The study was conducted at labor-room of IPGMER Hospital, Kolkata for consecutive 500 singleton deliveries at term ...

Aim: The purpose of this study was to assess whether the intrapartum amnioinfusion (AI) in the presence of meconium-stained amniotic fluid (MSAF) influence the rate of cesarean section and perinatal outcome. Material and methods: The investigated group consisted of 405 pregnant women in labor with meconium-stained amniotic fluid: 163 had performed AI, and 242 constituted a control group (withou...

We have studied risk factors for perinatal asphyxia among babies fulfilling the inclusion criteria and compared them with matched controls. Maternal or antepartum factors included were maternal age, gestational age, hypertension, diabetes mellitus and antenatal clinic (ANC) visits less than 3. Intrapartum factors included malpresentation, mode of delivery, meconium stained amniotic fluid, Chori...

Background: Since it is not always possible clinically and radiographically to predict the development of meconium aspiration syndrome (MAS) in infants born with meconium-stained amniotic fluid, there a need for biomarkers that may MAS these infants. Methods: The study was planned Ankara Zekai Tahir Burak Gynecology Hospital. Among term (>37 gestational weeks) from mothers who had Meconium-Stai...