objective(s):transplantation quality improvement and reduction of cellular damage are important goals that are now considered by researchers. melatonin is secreted from the pineal gland and some organs such as testes. according to beneficial effects of melatonin (such as its antioxidant and antiapoptotic properties), researchers have proposed that the use of melatonin may improve transplantatio...

objective: nutrients and antioxidants in the medium of immature oocyte have a profound effect on maturation, fertilization and development of resulting embryos. in this study the effects of melatonin as an antioxidant agent on maturation, glutathione level and expression of high mobility group box-1 (hmgb1) gene were evaluated in immature oocytes of mice stained with brilliant cresyl blue (bcb)...

multiple sclerosis is an autoimmune disease of the central nervous system which is accompanied by demyelinating the neurons. the imbalance between the t cell effectors and t cell regulators is thought to have a role in the pathogenesis of the disease. melatonin is a hormone that is secreted by pineal gland which has an important role in circadian rhythm and immune-modulatory effects. melatonin ...

This study investigated B16F10 melanoma cell death induced by melatonin combined with endoplasmic reticulum (ER) stress through the PI3K/Akt/mTOR pathway. Cell viability was significantly decreased after treatment with melatonin combined with ER stress from thapsigargin or tunicamycin compared to no treatment or treatment with melatonin only. Combined melatonin and ER stress also significantly ...

background: this study was conducted to evaluate the effect of melatonin on semen quality and quantity changes and increase of reproductive efficiency in lori-bakhtiari ram in the non-reproductive season. objectives: the purpose of this study was to investigate the effect of melatonin on testicular size and semen qualitative and quantitative changes in the non-breeding season is lori-bakhtiari ...

background and aims. melatonin is a circulating hormone that is mainly released from the pineal gland. it possesses antioxidant, free-radical scavenging, and immune-enhancing properties. a growing number of studies reveal a complex role for melatonin in influencing various diseases, including diabetes and periodontal diseases. the aim of this study was to examine the possible links between sali...

Brain or blood plasma melatonin was analysed as a measure for pineal melatonin production in sea bream. Access to calcium was limited by diluting the seawater to 2.5 per thousand and removing calcium from the diet or by prolonged feeding of vitamin D-deficient diet. Interactions/relations between melatonin and calcium balance and the hypercalcemic endocrines PTHrP and calcitriol were assessed. ...

Brain or blood plasma melatonin was analysed as a measure for pineal melatonin production in sea bream. Access to calcium was limited by diluting the seawater to 2.5& and removing calcium from the diet or by prolonged feeding of vitamin D-deficient diet. Inter­ actions/relations between melatonin and calcium balance and the hypercalcemic endocrines PTHrP and calcitriol were assessed. Restrict­ ...

Background: Melatonin is a hormone secreted by the pineal gland in the brain. It helps regulate other hormones and maintains the body’s daily rhythm, telling us when to fall asleep and when to wake up. Ever since we developed electricity and the lightbulb, we have been decreasing our body’s secretions of melatonin by being exposed to bright light after it is dark. Jet lag, shift work and poor v...