Purpose: To investigate the anti-urolithiatic activity of the aqueous and alcoholic extracts of Melia azedarach Linn leaves in calcium oxalate urolithiasis in male albino rats. Methods: The effect of oral administration of aqueous and ethanol extracts of Melia azedarach Linn leaves on calcium oxalate urolithiasis has been investigated. Lithiasis was induced by oral adminstration of ethylene gly...

OBJECTIVE To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach (M. azedarach) L. (Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains. METHODS Petrol, benzene, ethyl acetate, methanol, and aqueous extracts at five different concentrations (1, 2, 5, 10 and 15 mg/mL) were evaluated. Disk diffusion method was ...

Antimicrobial efficiency of Melia azedarach L. a medicinal plants (leaf extracts) were examined using Methanol, Ethanol, Petroleum ether and water, as solvents and tested against eight human pathogens like Bacteria: Bacillus cereus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Fungi: Aspergillus niger, Aspergillus flavus, Fusarium oxisporum, Rhizopus stolonifer using agar we...

Background: Melia indica and M. azedarach (Meliaceae) are widely used in traditional medicine. These species are considered as natural pesticides. Their major compound is azadirachtin (AZD) which is considered as the marker for quality control of these species. Objective: In the present investigation, AZD content of the leaves and fruits (comprising the whole fruit, peel, pulp and seeds) of M....

Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 microM and 20 microM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.

From the methanol extract of Penicillium sp. cultivated on sterilized rice for three weeks we isolated three new meroterpenes preaustinoid A1, A2 and B1. The fungus was isolated from the root bark of Melia azedarach after surface sterilization. The structures of these compounds were identified by intensive spectroscopic studies.

Melia azedarach L. has been utilized in traditional systems of medicine for the treatment various diseases including urolithiasis. The study aimed to perform phytochemical studies and anti-urolithiatic potential fruit-seed extracts azedarach. Sequential extraction was performed using chloroform, methanol water. plant were then subjected quantitative tests analysis. An activity investigated via ...

Macrophomina phaseolina (Tassi) Goid is a soil-borne fungal pathogen that causes root rot disease in more than 500 plant species but no registered fungicide is available for its control. The present study was carried out to investigate the antifungal activity of aqueous leaf extracts of Azadirachta indica A. Juss., Melia azedarach L. and Toona ciliata Roxb. (Meliaceae) against M. phaseolina. Aq...

A crude acetone extract and oil of ripe fruits from Melia azedarach L. were evaluated against the 2nd and 4th instar larvae of Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae). Both oil and extract exhibited highly significant growth inhibition at all concentrations tested, while the oil of M. azedarach recorded higher insecticidal activity against both instars than the crude extract. GC...