BACKGROUND Breast cancer susceptibility may be modulated partly through polymorphisms in oxidative enzymes, one of which is myeloperoxidase (MPO). Association of the low transcription activity variant allele A in the G463A polymorphism has been investigated for its association with breast cancer risk, considering the modifying effects of menopausal status and antioxidant intake levels of cases ...

objective the aim of this study was to determine the effect of revival soymilk consumption and moderate exercise on vasomotor symptoms, total antioxidant capacity (tac) and alkaline phosphates activity in postmenopausal women. materials and methods in this study, daily for 3 months, 37 postmenopausal women (mean age = 52.2± 4.6 years) were randomly assigned to soymilk (n=15), exercise +soymilk ...

A retrospective review was done to evaluate the importance of degenerative endometrial debris accompanied with benign-looking endometrial cells in Papanicolaou (Pap) smears. In total, 306 patients were divided into 2 groups according to the absence (group 1) or presence (group 2) of endometrial debris. Eighty-one (26.5%) patients received histologic follow-up. The biopsy rate for premenopausal ...

Blood pressure variability represents an independent risk factor for cardiovascular diseases. To detect possible blood pressure variability changes from fertile to menopausal status, we enrolled consecutively 219 women: 104 fertile women (46.6 +/- 3.4 years) and 115 menopausal women (53.9 +/- 3.98 years). We evaluated for each patient the body mass index (BMI), 24 h, daytime, night-time systoli...

OBJECTIVE Hormonal changes during menopausal transition are linked to physical and psychological symptoms' emergence. This study aims to explore if life events predict menopausal symptoms. METHODS This cross-sectional research encompasses a community sample of 992 women who answered to socio-demographic, health, menopause-related and lifestyle questionnaires; menopausal symptoms and life even...

Polycystic ovary syndrome (PCOS), a common reproductive endocrine condition manifests at puberty, and is characterized by hyperandrogenism, chronic anovulation, and obesity. PCOS cases exhibit an adverse coronary heart disease (CHD) profile at an early age, including insulin resistance, dyslipidemia and increased central adiposity. It can be hypothesized that the menopausal transition, whether ...

INTRODUCTION Breast cancer is the second leading cancer in Korean women. To assess potential genetic associations between the prostate stem cell antigen (PSCA) gene in the chromosome 8q24 locus and breast cancer risk in Korean women, 13 SNPs were selected and associations with breast cancer risk were analyzed with reference to hormone receptor (HR) and menopausal status. METHODS We analyzed D...