Monocytes and macrophages utilize the class A and B scavenger receptors to recognize and perform phagocytosis of invading microbes before a pathogen-specific immune response is generated. HIV-1 Nef protein affects the innate immune system impairing oxidative burst response and phagocytic capacity of macrophages. Our data show that exogenous recombinant myristoylated Nef protein induces a marked...

Knowledge about the argumentative structure of scientific articles can, amongst other things, be used to improve automatic abstracts. We argue that the argumentative structure of scientific discourse can be automatically detected because reasordng about problems, research tasks and solutions follows predictable patterns. Certain phrases explicitly mark the rhetorical status (communicative funct...

Macrophages play a central role in the pathogenesis of inflammatory and fibrotic lung diseases. However, alveolar macrophages (AM) are poorly available in humans to perform in vitro studies due to a limited access to broncho-alveolar lavage (BAL). In this study, to identify the best alternative in vitro model for human AM, we compared the phenotype of AM obtained from BAL of patients suffering ...

this study tries to show that how viewpoint functions in discourse. as it will be clarified, it is highly related to the intention of the speaker/writer, and as a result, the orientation (s)he adopts in the discourse. deictic markers function as discourse markers to fix and anchor time, place, agent, and other discursive elements. in this way, the viewpoint adopted by the enunciator/utterer is ...

[Background] The key to integrated watershed management is take simultaneous account of environmental, economic, and social development goals; hence, a multi-objective decision making approach required. However, our understanding application in remains limited. [Objective] objective this study was develop system (MDMS) that could simultaneously handle multiple problems objectives small based on...

Meta-language utterances, i.e. utterances about other utterances, are ubiquitous in every type of human discourse, from unconstrained multi-party conversations to task-oriented man-machine dialogues. Several examples of meta-language communication are analyzed, identifying the complexities that a cognitively plausible discourse model should address. Meta-language utterances are investigated in ...

At present, discourse parsing is an important research topic. Rhetorical Structure Theory (RST) is one of the most popular approaches in this field. In general, discourse parsing includes three stages: discourse segmentation, discourse relations detection and building up rhetorical trees. Different strategies are used when developing discourse parsers. One of the strategies to detect discourse ...

HIV-1 infection of peripheral blood monocyte-derived macrophages (MDMs) is unrelated to the level of CD4 expression on the surface of the cell, is associated with considerable donor variability, causes minimal cytopathology, and results in peak viral antigen production after 2 weeks of infection. Phagocytosis of opsonized Candida albicans by MDMs infected in vitro with several strains of HIV wa...