Dezfulian C, Shojania K, Collard HR, et al. Subglottic secretion drainage for preventing ventilator-associated pneumonia: a metaanalysis. Am J Med 2005;118:11–8. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

OBJECTIVE To evaluate the success and failure, apical sealing and biocompatibility of silver amalgam, IRM, SuperEBA and MTA as retrograde filler materials. STUDY DESIGN A metaanalysis is made of filler materials in periapical surgery, evaluating a total of 30 articles published in recent years. RESULTS Percentage success with silver amalgam was 76.5% and slightly inferior to that afforded b...

OBJECTIVE To compare the clinical efficacy of certolizumab pegol (CZP) with that of other anticytokine agents indicated for the treatment of rheumatoid arthritis (RA) with identical therapeutic indication (anti-tumor necrosis factor-α, anti-interleukin 1 or 6), with the objective of determining the noninferiority of CZP. METHODS A systematic review was performed to identify randomized control...

Top Introduction Historical notes The unacceptable face of... Narrative reviews Limitations of a single... Epidemiology of results A more transparent appraisal Cumulative meta-analysis References The number of papers published on meta-analyses in medical research has increased sharply in the past 10 years (fig 1). The merits and perils of the somewhat mysterious procedure of metaanalysis, howev...