BACKGROUND Socio-behavioral consulting centers offer methadone maintenance therapy which is a very useful method for drug dependents. These centers offer a wide range of services like education, consulting, prevention, care taking of patients and treatment for high risk groups such as AIDS-infected patients. Methadone maintenance therapy (MMT) is helpful in harm minimization and increasing the ...

CONTEXT Despite evidence that methadone maintenance treatment (MMT) is effective for opioid dependence, it remains a controversial therapy because of its indefinite provision of a dependence-producing medication. OBJECTIVE To compare outcomes of patients with opioid dependence treated with MMT vs an alternative treatment, psychosocially enriched 180-day methadone-assisted detoxification. DE...

background and aims: sexual dysfunction is a common complaint among drug abusers in the treatment with methadone and buprenorphine. the aim of this study was to assess sexual dysfunction in patients undergoing methadone or buprenorphine for maintenance therapy. methods: this research was a cross-sectional study. a 3-parts questionnaire (demographic questions, international index of erectile fun...

- Methadone, a synthetic opioid agonist, is commonly used for the treatment of heroin dependence. Depending on how alcohol addiction is defined, rates of alcoholism vary among those attending methadone maintenance treatment (MMT) programmes. Most of the current literature has shown that alcohol consumption increases during medium- or long-term MMT. However, up to now, no data have been reported...

Injection drug use (IDU) continues to be a significant public health issue in the U.S. and internationally, and there is evidence to suggest that the burden of injection drug use and associated morbidity and mortality falls disproportionately on minority communities. IDU is responsible for a significant portion of new and existing HIV/AIDS cases in many parts of the world. In the U.S., the prev...

MMT (Methadone maintenance treatment) is an effective way to treat opioid dependence. In Portugal, an MMT program has been available in pharmacies since January 1998, when a formal agreement was signed by the IDT, I.P. (Institute on Drugs and Drug Addiction), the PPS (Portuguese Pharmaceutical Society), and the ANF (National Association of Pharmacies). In January 2004, the INFARMED (National Au...

This paper investigates some productive ambiguities around the medical administration of methadone in the Republic of Ireland. The tensions surrounding methadone maintenance therapy (MMT) are outlined, as well as the sociohistorical context in which a serious heroin addiction problem in Ireland developed. Irish psychiatry intervened in this situation, during a time of institutional change, deba...

background: clopidogrel is a prodrug that converts in the liver to an active thiol metabolite, which irreversibly inhibits the platelet p2y12 adenosine diphosphate receptor. it seems that methadone as cyp2c19 inhibitor affects ticlopidine activity in vivo. this study aimed to test the ability of methadone in changing ticlopidine pharmacokinetics. methods: we conducted a case–control study in 10...

to evaluate the effectiveness of a relapse prevention cognitive-behavioral model, based on marlatt treatment approach, in opioid-dependent patients participating in the methadone maintenance treatment (mmt) in iran.the study consisted of 92 individuals treated with methadone in iranian national center of addiction studies (incas). participants were randomized into two groups: educational interv...