The anticoagulant racemic warfarin is synthesized by the Michael addition of 4-hydroxycoumarin with benzalacetone in the present of equimolar amounts of imidazolium based ionic liquids [bmim] BF4 and [bmim] Br and other reaction solvents such as H2O, pyridine and ammonia in five different tests. Also synthesis of a derivative of warfarin (2-methyl-4-phenyl pyrano [3, 2-c] chromen-5(4H)-one) und...

michael addition of pyrimidine and purine nucleobases to substituted as well as unsubstituted α,β-unsaturated esters efficiently proceeds in the presence of catalytic amount of zinc oxide in ionic liquid 1-butyl-3-methylimidazolium bromide (zno/[bmim]br) under microwave irradiation to afford carboacyclic nucleosides, as biologically important compounds, in good to excellent yields and in short ...