We present modeling and analysis for the static behavior and collapse instabilities of doublyclamped and cantilever microbeams subjected to capillary forces. These forces can be as a result of a volume of liquid trapped underneath the microbeam during the rinsing and drying process in fabrication. The model considers the microbeam as a continuous medium, the capillary force as a nonlinear funct...

Presented here is a novel microbeam technology--the Flow-And-ShooT (FAST) microbeam--under development at RARAF. In this system, cells undergo controlled fluidic transport along a microfluidic channel intersecting the microbeam path. They are imaged and tracked in real-time, using a high-speed camera and dynamically targeted, using a magnetic Point and Shoot system. With the proposed FAST syste...

In this paper, the snap-through buckling of an initially curved microbeam subject to an electrostatic force, accounting for fringing field effect, is investigated. The general governing equations of the curved microbeam are developed using Euler-Bernoulli beam theory and used to develop a new criterion for the snap-through buckling of that beam. The size effect of the microbeam is accounted for...

Since 2003, we use the GSI heavy-ion microprobe to irradiate living cells with ions from the UNILAC [1]. Two specific properties of the microbeam method make it stand out among other, more conventional irradiation procedures: First, we precisely control the dose by counting and switching individual particles that are to be delivered to the target, down to the low-dose limit of a single ion per ...

We have developed a compact microbeam radiation therapy device using carbon nanotube cathodes to create a linear array of narrow focal line segments on a tungsten anode and a custom collimator assembly to select a slice of the resulting wedge-shaped radiation pattern. Effective focal line width was measured to be 131 μm, resulting in a microbeam width of ∼300 μm. The instantaneous dose rate was...

Branch position in the moss Physcomitrella patens is regulated by blue light. In this study, fluence rate dependency of branch position determination was investigated by partial cell irradiation with a microbeam. With a 30 Wm(-2) or lower fluence rate, branches formed at the microbeam area, but formed outside the microbeam when the fluence rate was raised to > or = 200 Wm(-2). Thus, both weak a...

The TIARA facilities of JAEA in Takasaki is equipped with a several-MeV light-ion and a several-dozen-MeV heavy-ion microbeam formation systems of focusing type, and a several-hundred-MeV heavy-ion microbeam formation system of collimating type. The microbeams with a spot size of 1 μm or less in diameter are extensively utilized for the research in materials science and biotechnology. An in-air...

Single-cell microbeam irradiators are of increasing interest to the biological community. The 5th International Workshop on Microbeam Probes of Cellular Radiation Response, which took place in Stresa, Italy, in May 2001, was attended by about 120 registrants, roughly evenly divided between physicists and biologists. Many new microbeam devices are now under development, and there has been a sign...

(6 ) Swyt, C. R. Fiori, C. E. Microbeam Analysis-1986; San Francisco Press: San Francisco, CA, 1986; p 482. (7) Myklebust, R. L.; Marinenko, R. B.; Newbury, D. E.; Bright. D. S. Microbsem Analysis1985; Sen Francisco Press: San Francisco, CA, 1985; p 101. (6 ) Mayr, M.; Angeili, J. X-Ray Spectrom. 1985, 14, 89. (9) Ono, Y.; Nbken, C. H.; Tagata, S.; Seo, Y. Microbeam Anawsis1985; San Francisco P...