INTRODUCTION This study analyses the diagnostic value of ultrasonography (US) detection for calcification in thyroid nodules. MATERIALS AND METHODS We analysed the preoperative US findings and clinical characteristics of 577 malignant and 3434 benign thyroid patients who underwent surgery in our hospital. RESULTS The malignant rate in patients with microcalcification hyperechoic and tiny ca...

The presence of microcalcification clusters (MCs) in mammogram is a major indicator of breast cancer. Detection of an MC is one of the key issues for breast cancer control. In this paper, we present a highly accurate method based on a morphological image processing and wavelet transform technique to detect the MCs in mammograms. The microcalcifications are firstly enhanced by using multistructu...

Early detection is the key to improve breast cancer prognosis. The only proven effective method of breast cancer early detection is mammography. An early sign of 30-50% of breast cancer is the appearance of clusters of fine, granular microcalcifications and 60-80% of breast carcinomas reveal microcalcification clusters upon histological examination. The high correlation between the appearance o...

Currently, mammography is recognized as the most effective imaging modality for breast cancer screening. The challenge of using mammography is how to locate the area, which is indeed a solitary geographic abnormality. In mammography screening it is important to define the risk for women who have radiologically negative findings and for those who might develop malignancy later in life. Microcalc...

PURPOSE Stereotactic vacuum-assisted breast biopsy (VAB) has been established as a standard method for histological diagnosis of microcalcification or nonpalpable breast lesions on mammography. Generally, the procedure has been done under the prone position or upright sitting position. We herein attempt to evaluate clinical utility of Stereotactic VAB under lateral decubitus position. METHODS...

Breast microcalcifications play an essential role in the detection and evaluation of early breast cancer in clinical diagnostics. However, in digital mammography, microcalcifications are merely graded with respect to their global appearance within the mammogram, while their interior microstructure remains spatially unresolved and therefore not considered in cancer risk stratification. In this a...

Structural texture measures are used to address three aspects of early detection of breast cancer in screening mammograms: detection of microcalcification, detection and classification of clustered microcalcification as benign or malignant, and the detection of invasive lobular carcinoma. The use of structural texture features replaces the task of initial detection of complex and poorly modelle...

In order to develop an accurate computer-aided diagnosis system for the automatic detection of microcalcification clusters in mammograms. In this study, we presented a new microcalcification clusters detection method by using Gaussian Markov Random Fields (GMRFs) representation. The design and evaluation of the algorithm involved three main phases. In the first phase of the algorithm, a trainin...

AIMS Parenchymal microcalcification in the brain coincides with neurodegenerative diseases, but is also frequently found in neurologically normal individuals. The origin and role of this process are still under debate. Parvalbumin (PV) is a protein acting as a Ca(2+) buffer and Ca(2+) shuttle towards intracellular Ca(2+) sinks, like mitochondria and the endoplasmic reticulum. Constitutively, it...

Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and mortality. Positron emission tomography and X-ray computed tomography (PET/CT) imaging of atherosclerosis using (18)F-sodium fluoride ((18)F-NaF) h...