Microfluidic-based biochips are soon revolutionizing clinical diagnostics and many biochemical laboratory procedures due to their advantages of automation, cost reduction, portability, and efficiency [18]. Conventional technology depends on the manipulation of continuous liquid flow through microfabricated channels. However, actuation of flow is implemented with external assistance of micro-pum...

When integrated into microfluidic chips, ion-selective nanoporous polymer and solid-state membranes can be used for on-chip pumping, pH actuation, analyte concentration, molecular separation, reactive mixing, and molecular sensing. They offer numerous functionalities and are hence superior to paper-based devices for point-of-care biochips, with only slightly more investment in fabrication and m...

   Historically, DNA molecules have been known as the building blocks of life, later on in 1994, Leonard Adelman introduced a technique to utilize DNA molecules for a new kind of computation. According to the massive parallelism, huge storage capacity and the ability of using the DNA molecules inside the living tissue, this type of computation is applied in many application areas such as me...

Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. As more bioassays are executed concurrently on a biochip, system integration and design complexity are expected to increase dramatically. Current techniques for full-custom design of digital microfluidic biochips however do not scale we...

Digital microfluidic biochips (DMFBs) are revolutionizing many biochemical analysis procedures, e.g., high-throughput DNA sequencing and point-of-care clinical diagnosis. However, today’s DMFBs suffer from several limitations: (1) constraints on droplet size and the inability to vary droplet volume in a fine-grained manner; (2) the lack of integrated sensors for real-time detection; (3) the nee...

Microfluidics-based biochips, also referred to as lab-on-a-chip (LoC), are devices that integrate fluid-handling functions such as sample preparation, analysis, separation, and detection. This emerging technology combines electronics with biology to open new application areas including point-of-care diagnosis, on-chip DNA analysis, and automated drug discovery. As digital microfluidic biochips ...

Highly ordered radially aligned microchannels are produced on the surface of polymer nanocomposite thin films via droplet evaporation. This simple, rapid, and cost-effective approach opens a new avenue for producing macroscopic surface patterns that have potential as scaffolds or substrates in the field of microelectronics or microfluidic-based biochips.