Objective(s): Recent studies revealed that microRNAs (miRNAs) may play crucial roles in the responses and pathologic processes of spinal cord injury (SCI). This study aimed to investigate the effect and the molecular basis of miR-103 on LPS-induced injuries in PC12 cells in vitro and SCI rats in vivo. Materials and Methods: PC12 cells were exposed to LPS to induce cell injuries to mimic the in ...

This paper considers the simple step-stress model from the Marshall-Olkin generalized exponential distribution when there is time constraint on the duration of the experiment. The maximum likelihood equations for estimating the parameters assuming a cumulative exposure model with lifetimes as the distributed Marshall Olkin generalized exponential are derived. The likelihood equations do not lea...

The tonalness spectrum shows the likelihood of a spectral bin being part of a tonal or non-tonal component. It is a non-binary measure based on a set of established spectral features. An easily extensible framework for the computation, selection, and combination of features is introduced. The results are evaluated and compared in two ways. First with a data set of synthetically generated signal...

Response 4: The introduction will be changed to contain: Sussmann et al. 2013 did a similar study on the inter-comparison of methane from MIR and NIR retrievals. They used a Tikhonov-L1 regularized profile retrieval scheme with the standard NDACC retrieval package SFIT2 for the MIR and the standard TCCON retrieval (GFIT) for the NIR spectra. They conclude that the obtainable information from th...

here, a predator-prey model with hassell-varley type functional responses is studied. some sufficient conditions are obtained for the permanence and global asymptotic stability of the system by using comparison theorem and constructing a suitable lyapunov functional. moreover, an example is illustrated to verify the results by simulation.

Evaluating solutions to many music IR problems – such as playlist generation, music similarity – in absence of formal evaluation measures frequently requires user studies to establish the benefits of one solution over the other. Building an according application framework to deploy and test user responses is a cumbersome and complex task. We present Clubmixer an advanced client-server based aud...

In this paper we use a class of stochastic functional Kolmogorov-type model with jumps to describe the evolutions of population dynamics. By constructing a special Lyapunov function, we show that the stochastic functional differential equation associated with our model admits a unique global solution in the positive orthant, and, by the exponential martingale inequality with jumps, we dis...

It is proved that any static system that is spacetime-geodesically complete at infinity, and whose spacelike-topology outside a compact set is that of R minus a ball, is asymptotically flat. The matter is assumed compactly supported and no energy condition is required. A similar (though stronger) result applies to black holes too. This allows us to state a large generalisation of the uniqueness...

Background and Objective: Ulcerative colitis (UC) is an unknown recurrent intestinal disease and a common cause of gastrointestinal disorders, which may lead to colorectal cancer if not diagnosed and treated in a timely manner. The beneficial effects of several probiotics in diseases like inflammatory bowel disease (IBD) have been investigated, although their mechanisms have not been yet fully ...