Pregnancy has different meanings to different women depending upon their circumstances. A number of qualitative studies have described the experience of miscarriage by women who had desired to carry their pregnancy to full term. The aim of this meta-analysis was to identify a scale of psychological reaction to miscarriage. Meta-analysis is a quantitative approach for reviewing articles from sci...

BACKGROUND Approximately half of recurrent miscarriages have unexplained etiology. Recent evidences suggest that cytokines are important determinants in pregnancy maintenance and as such, cytokine gene polymorphisms, which can affect cytokine production and/or functionality, could play a role in the disorder. Thus, we aimed to investigate the association of selected cytokine gene polymorphisms ...

Aims: To investigate women’s perceptions of miscarriage and its complications. Study Design: A qualitative design was used with data collected through semistructured interviews. Place and Duration of Study: Gynaecology ward of the Queen Elizabeth Central Hospital, Blantyre, Malawi, during February and March 2012. Methodology: Sample: We included 30 patients (aged between 18 and 39) admitted to ...

BACKGROUND Dehydroepinadrosterone (DHEA) supplementation improves pregnancy chances in women with diminished ovarian reserve (DOR), by possibly reducing aneuploidy. Since a large majority of spontaneous miscarriages are associated with aneuploidy, one can speculate that DHEA supplementation may also reduce miscarriage rates. METHODS We retroactively compared, utilizing two independent statist...

Recurrent miscarriage affects 1% of all couples attempting pregnancy. Immunological factors are postulated to play a role in the aetiology of recurrent miscarriage because the fetus and placenta are immunologically different from the mother. In particular, altered expression of the, non-classical, class I histocompatibility leukocyte antigen (HLA) molecules has been postulated to play a role in...

Activated protein C (APC) resistance, both in its congenital form, due to the factor V Leiden mutation, and in its acquired form, are important risk factors for systemic venous thrombosis. In view of the suspected thrombotic aetiology of some cases of recurrent miscarriage, the prevalence of APC resistance was determined among 1111 consecutive Caucasian women with a history of either recurrent ...

OBJECTIVE To determine whether a history of miscarriage is related to birth experience and/or maternal fear of an adverse birth outcome for self or infant during a subsequent delivery. DESIGN Secondary analysis of a prospective cohort study, the First Baby Study. SAMPLE Women age 18 to 35 who were expecting to deliver their first live-born infants in Pennsylvania between January 2009 and Ap...

OBJECTIVE To evaluate anti-Mullerian hormone, basal follicle stimulating hormone, luteinizing hormone, estradiol, and female age in women with recurrent miscarriage and to compare women with explained and idiopathic recurrent miscarriage. DESIGN Retrospective cohort study. SETTING University hospital, tertiary care center. PATIENTS Women with recurrent miscarriage (78 explained, 66 idiopa...