This study was aimed at developing proposals and recommendations for optimizing the diagnostic process predicting outcomes of non-developing pregnancy. The developed algorithm allows using safest most informative methods to reliably determine functional state uterine endometrium mechanisms implantation disorders in patients with missed miscarriage.

Background: Study question: what is the effect of advanced aged in pregnant women using assisted reproductive technology on the rate of miscarriages? Summary answer: the advanced age effects on the rate of miscarriages. What is known already: It is well known that miscarriage risk increases with age. The proportion of women giving birth after 35 years of age has risen considerably in developing...

BACKGROUND There has been recent evidence suggesting the presence of anti-thyroid peroxidase antibodies (TPOAb) increases the risk of miscarriage, and levothyroxine can rescue miscarriages associated with TPOAb. We propose the most clinically pragmatic cohort to screen for TPOAb are women presenting for management of a missed miscarriage and have never birthed a liveborn. We measured serum TPOA...

Background and objective: The objective of this work is to match the security effectiveness two treatment modalities (Misoprostol versus Letrozol with Misoprostol) in medical 1st trimesteric missed miscarriages. Methods: This an interventional randomized case-control investigation that was performed at outpatient antenatal care clinic Luxor General Hospital during period from February December ...

Background: Despite the high prevalence of miscarriage, there are few studies which assess concordance a diagnosis miscarriage in routinely collected health databases. Objectives: To determine agreement and accuracy for between electronic records (EHR), Hospital Inpatient-Enquiry (HIPE) system, hospital register books Ireland. Methods: This is retrospective study comparing three data sources fr...

A familial Robertsonian translocation 15/22 was ascertained through a female carrier whose four pregnancies ended in missed abortions. Eleven 15/22 translocation carriers were detected in three generations among 23 family members investigated. The four proven female carriers, apart from the proposita, have miscarried seven out of 14 pregnancies. The kindred suggests that the 15/22 translocation...

Many women experience miscarriage every year. Every fourth woman who has given birth reports that she has previous experience of miscarriage. In a study of all women in the Swedish Medical Birth Register 1983-2003, we found that the number of cases of self reported miscarriage had increased in Sweden during this 21 year period. This increase can be explained by the introduction of sensitive pre...

The impact of abnormal placental karyotype on the inflammatory response within the villous tissue and peripheral circulation of women with miscarriage was evaluated. Villous (n = 38) and venous blood samples (n = 26) were obtained from women with missed miscarriage. Tissue chromosome analysis indicated 23 abnormal and 15 normal karyotypes. Concentration of tumour necrosis factor alpha (TNFα), T...