Background The house dust mites are cosmopolitan guest in human habitation. Dust mites occur in nearly all homes. They are generally found in pillows, bed sheets, mattress, stuff toys, carpets etc. Dust mites feed on organic detritus such as flakes of shed human skin and flourish in stable environment of dwellings. Exposure to house dust mites is recognized as major cause allergy worldwide. The...

This study was concerned with the correlation between skin test, bronchial provocation test, and histamine release from leucocytes and the serum level of total and allergen-specific IgE in patients atopic to house-dust mite allergen (Dermatophagiodes pteronyssinus) as measured by an intracutaneous skin test. It is concluded that, assuming a positive provocation test to be evidence of allergy, e...

House dust mite allergy is present in up to 90% of Asian atopic patients, with increasing incidence and prevalence of sensitization and clinical allergy from childhood through to adulthood. This far exceeds the reported prevalence of 50%–70% in Western populations [1]. House dust mite allergy is particularly common in the tropical areas of Southeast Asia due to the warm, humid climate [2]. In c...

House dust mite (HDM) represents one of the most common sources of aeroallergens worldwide and more than 50% of allergic patients are sensitized to these allergenic molecules. HDM allergy research in the past has been mainly focused on adaptive, mite allergen-dependent immune responses. In recent years it has become clear that, although the allergen-specific CD4+ Th2 cells orchestrate HDM aller...

The prevalence of allergic diseases, especially asthma and allergic rhinitis, has dramatically increased during the last decades. Mite and cockroach, which are the most common allergens in house dust, are the major indoor allergens in asthmatic and allergic rhinitis patients. The aim of this study was to compare the association between age of dwelling and some other home characteristics in asth...

Exposure to indoor allergens is an important risk factor for sensitisation and respiratory allergy. The aim of this paper was to evaluate the levels of mite, cat and latex allergens in dust collected from an indoor workplace and to assess whether the exposure to these allergens was associated with the allergy symptoms reported by employees. Sixty dust samples were collected. Allergen concentrat...

Background Risk factors which promote the development of allergy to the cow milk protein in infants include antenatal sensitization, bottle feeding of neonates, early start of bottle or mixed feeding, postnatal sensitization of mite and pollen allergy. The aim of the study was to analyze a family history of the allergic diseases, course of pregnancy and delivery in mothers, effect of concomitan...

PURPOSE OF REVIEW Animal models published within the past 18 months on asthma, food allergy and anaphylaxis, all conditions of rising public health concern, were reviewed. RECENT FINDINGS While domestic animals spontaneously develop asthma, food allergy and anaphylaxis, in animal models, divergent sensitization and challenge routes, dosages, intervals and antigens are used to induce asthmatic...

Background Infants with family history of atopy are considered at high risk for developing allergic disease. Environmental exposures are modifiable risk factors with a potential for intervention to prevent allergy. Children who develop house dust mite (HDM) sensitisation by pre-school age are at higher risk of developing asthma. Prevention of HDM sensitisation in early childhood by immune modul...