The origin of the improved performance Molecular Imprinted Polymers (MIPs) prepared by Nitroxide-Mediated Radical Deactivation Reversible Polymerization (NMRP) and conventional Free (FRP) was investigated through a detailed interpretation adsorption onto imprinted- non-imprinted materials. MIPs designed for 3,5-dichlorohydroxyacetophenone (DCHA) were copolymers methacrylic acid styrene cross-li...

A new approach is proposed for the synthesis of molecularly imprinted polymers (MIPs) (synthetic antibodies) as soluble nanogels with sizes close to the size of real antibodies. To imprint a molecular memory in particles consisting of only a few polymer chains, an initiator carrying multiple iniferter moieties is used. This allows for the simultaneous initiation of several polymer chains, and y...

in this study, aniline-formaldehyde polymer was synthesized and then modified with extra aniline as cross-linker in the presence and absence of ni(ii) as the template to produce ion imprinted poly(aniline-formaldehyde) (iipaf) and non imprinted poly(aniline-formaldehyde)(nipaf) the iipaf was subjected to adsorption, preconcentration and determination of ni(ii) ion in environmental samples. the ...

Molecularly imprinted polymers (MIPs) represent a new class of materials possessing high selectivity and affinity for the target molecule. They have been utilized as sensors, catalysts, sorbents for solid-phase extraction, stationary phase for liquid chromatography, mimics of enzymes, receptors, and antibodies. In this research, molecular imprinted polymers (MIPs) for luteolin were prepared usi...

Molecular recognition processes found in nature have always inspired scientists to mimic these systems in synthetic materials such as molecular imprinted polymers. Selective receptors within a polymer have a huge range of applications such as in separation processes, analytical chemistry, sensors, catalysis, drug discovery and therapeutics. In this last area in particular, polymers are having a...

Molecular imprinting is a technique for preparing polymer scaffolds that function as synthetic receptors. Imprinted polymers that can selectively bind organic compounds have proven useful in sensor development. Although creating synthetic molecular-imprinting polymers that recognize proteins remains challenging, nanodevices and nanomaterials show promise in this area. Here, we show that arrays ...

This work has focused on the rational development of polymers capable of acting as traps of bile salts. Computational modeling was combined with molecular imprinting technology to obtain networks with high affinity for cholate salts in aqueous medium. The screening of a virtual library of 18 monomers, which are commonly used for imprinted networks, identified N-(3-aminopropyl)-methacrylate hydr...

Molecular recognition is a fundamental and ubiquitous process that is the driving force behind life. Natural recognition elements - including antibodies, enzymes, nucleic acids, and cells - exploit non-covalent interactions to bind to their targets with exceptionally strong affinities. Due to this unparalleled proficiency, scientists have long sought to mimic natural recognition pathways. One p...

Title of dissertation: MOLECULARLY IMPRINTED POLYMERS FOR THE SELECTIVE RECOGNITION OF PROTEINS Daniel S. Janiak, Doctor of Philosophy, 2009 Dissertation directed by: Professor Peter Kofinas Fischell Department of Bioengineering Molecular imprinting is a technique used to synthesize polymers that display selective recognition for a given template molecule of interest. In this study, the role of...

The aim of this work was to investigate the possibility of employing Molecularly Imprinted Polymers (MIPs) as a controlled release device for 5-fluorouracil (5-FU) in biological fluids, especially gastrointestinal ones, compared to Non Imprinted Polymers (NIPs). MIPs were synthesized using methacrylic acid (MAA) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as crosslinking ag...