We report strong evidence for a approximately 304 day periodicity in the spin history of the accretion-powered pulsar GX 1+4 that is most probably associated with the orbital period of the system. We have used data from the Burst and Transient Source Experiment on the Compton Gamma-Ray Observatory to show a clear periodic modulation of the pulsar frequency from 1991 to date, in excellent agreem...

Glycosylation is of importance for the structure and function of proteins. In the case of vitellin (Vt), a ubiquitous protein accumulated into granules as the main yolk protein constituent of oocytes during oogenesis, glycosylation could be of importantance for the folding, processing and transport of the protein to the yolk and also provides a source of carbohydrate during embryogenesis. Vt fr...

In spite of extensive efforts, even the most experienced laboratories dealing with isotopic measurements of atmospheric CO2 still suffer from poor inter-laboratory consistency. One of the complicating factors of these isotope measurements is the presence of N2O, giving rise to mass overlap in the isotope ratio mass spectrometer (IRMS). The aim of the experiment reported here has been twofold: f...

Context. BP Cru is a well known high-mass X-ray binary composed of a late B hypergiant (Wray 977) and a neutron star, also observed as the X-ray pulsar GX301-2. No information about emission from BP Cru in other bands than X-rays and optical has been reported to date in the literature, though massive X-ray binaries containing black holes can have radio emission from a jet. Aims. In order to ass...

The variability of the X-ray flux from the pulsar GX 301-2 is analyzed by using data from the ART-P telescope of the Granat Observatory. The intensity variations with time scales of several thousand seconds are studied at various orbital phases. The high-state flux from the source exceeds its low-state flux by as much as a factor of 10. The hardness and spectrum of the source are shown to chang...

Recent results of the spectral and timing analysis of X-ray pulsars in hard X-rays with the INTEGRAL observatory are reviewed. The evolution of the cyclotron line energy with the source luminosity was studied in detail for the first time for several sources. It was shown that for V0332+53 this dependence is linear, but for 4U0115+63 and A0535+262 it is more complicated. There are some evidences...

The variability of the X-ray flux from the pulsar GX 301-2 is analyzed by using data from the ART-P telescope of the Granat Observatory. The intensity variations with time scales of several thousand seconds are studied at various orbital phases. The high-state flux from the source exceeds its low-state flux by as much as a factor of 10. The hardness and spectrum of the source are shown to chang...

Previous studies with Gonadotropin Releasing Hormone (GnRH/LHRH) vaccines have demonstrated the usefulness of immunization against this hormone in prostate cancer. To this purpose, we generated the completely synthetic GnRHm1-TT peptide which has been validated in a proof of concept formulated together with Montanide ISA 51 adjuvant. Such vaccine preparation induced a significant anti-GnRH immu...