Technologies for decomposing the electromyographic (EMG) signal into its constituent motor unit action potential trains have become more practical by the advent of a non-invasive methodology using surface EMG (sEMG) sensors placed on the skin above the muscle of interest (De Luca et al 2006 J. Neurophysiol. 96 1646-57 and Nawab et al 2010 Clin. Neurophysiol. 121 1602-15). This advancement has w...

25 Synchronous motor unit firing instances have been attributed to anatomical inputs shared 26 by motoneurons. Yet, there is a lack of empirical evidence confirming the notion that common 27 inputs elicit synchronization under voluntary conditions. We tested this notion by measuring 28 synchronization between motor unit action potential trains (MUAPTs) as their firing rates 29 progressed from a...

Abstract Introduction Motor neuron loss is the primary pathologic feature of amyotrophic lateral sclerosis (ALS). An estimate number surviving motor units (MUs) represents a direct measure disease state in ALS. The objective study to compare MU estimation (MUNE) using multipoint stimulation method (MPS) and compound muscle action potentials (CMAP) amplitude patients with Methods Twenty-eight AL...

The aim of this paper is to introduce an extension to a force estimation technique based on activity index and to compare it to two other muscle force estimation techniques that also use the motor control information on the same set of surface EMG signals. Our new method is called motor unit twitch force technique and the compared methods include motor unit action potential rate and activity in...

Background: Electromyographic (EMG) signal decomposition is the process by which an EMG signal is decomposed into its constituent motor unit potential trains (MUPTs). A major step in EMG decomposition is feature extraction in which each detected motor unit potential (MUP) is represented by a feature vector. As with any other pattern recognition system, feature extraction has a significant impac...

Title: Muscle Strength and Size are Associated with Motor Unit Connectivity in Aged Mice In older adults, loss of muscle strength (dynapenia) and loss of muscle mass (sarcopenia) are important contributors to loss of physical function. We sought to investigate dynapenia, sarcopenia, and loss of motor unit function in aging mice. C57BL/6J mice were analyzed with cross sectional (males: 3 vs. 27 ...

Twelve subjects were classified as left-handed (LH) or right-handed (RH) using Annett's hand dominance classification. Motor unit recordings were obtained from the first dorsal interosseous (FDI) muscle of each hand using a quadrifilar needle electrode. Firing occurrences of individual motor units were then identified and the firing rates of all motor units recorded during the contraction were ...

The quantification of the bioelectric phenomena originating in nervous and muscular tissues is an essential task in diagnosis within the field of Electromedicine. Clinical electromyography is the part of Clinical Neurophysiology focused on the neuromuscular system, and includes the study of the electrical activity of peripheral nerves (electroneurography), striated muscles (electromyography, in...