نتایج جستجو برای: mouse endometrium

تعداد نتایج: 287710  

2012
Cheng-Chiu Huang Grant D. Orvis Ying Wang Richard R. Behringer

Endometrium is the inner lining of the uterus which is composed of epithelial and stromal tissue compartments enclosed by the two smooth muscle layers of the myometrium. In women, much of the endometrium is shed and regenerated each month during the menstrual cycle. Endometrial regeneration also occurs after parturition. The cellular mechanisms that regulate endometrial regeneration are still p...

2011
Yong Guo Bin He Xiangbo Xu Jiedong Wang

In our previous study, menstrual-like changes in mouse were provoked through the pharmacologic withdrawal of progesterone with mifepristone following induction of decidualization. However, mouse is not a natural menstruation animal, and the menstruation model using external stimuli may not truly reflect the occurrence and development of the human menstrual process. Therefore, we established a m...

Journal: :Human reproduction 2009
M-L Alvarez Gonzalez F Frankenne C Galant E Marbaix J-M Foidart M Nisolle A Béliard

BACKGROUND In vivo mouse models have been developed to study the physiology of normal and pathologic endometrium. Although angiogenesis is known to play an important role in endometrial physiology and pathology, the origin of neovasculature in xenografts remains controversial. The aim of this study was to assess the origin of the neovasculature of endometrial grafts in different mouse models. ...

Journal: :Development 2017
Matteo Boretto Benoit Cox Manuel Noben Nikolai Hendriks Amelie Fassbender Heleen Roose Frédéric Amant Dirk Timmerman Carla Tomassetti Arne Vanhie Christel Meuleman Marc Ferrante Hugo Vankelecom

The endometrium, which is of crucial importance for reproduction, undergoes dynamic cyclic tissue remodeling. Knowledge of its molecular and cellular regulation is poor, primarily owing to a lack of study models. Here, we have established a novel and promising organoid model from both mouse and human endometrium. Dissociated endometrial tissue, embedded in Matrigel under WNT-activating conditio...

Journal: :Endocrinology 2009
Tu'uhevaha J Kaitu'u-Lino David J Phillips Naomi B Morison Lois A Salamonsen

Abnormal uterine bleeding can severely affect the quality of life for women. After menstruation, the endometrium must adequately repair to limit and stop bleeding. Abnormal uterine bleeding may result from incorrect or inadequate endometrial repair after menstruation. Previous studies have shown an important contribution of activin to skin wound healing, with severely delayed wound repair obser...

Journal: :Human reproduction 2002
S Hague I Z MacKenzie R Bicknell Margaret C P Rees

BACKGROUND Progestogens are used clinically for contraception, to control excessive menstrual bleeding, and to prevent estrogen-induced endometrial hyperplasia. A significant problem with progestogen-only methods of contraception is the induction of breakthrough bleeding. METHODS The effects of different progestogens on angiogenesis were examined using two approaches. The mouse sponge angioge...

Journal: :journal of paramedical sciences 0
marzieh davoudi school of biology, damghan university, damghan,iran saeed zavareh school of biology, damghan university, damghan,iran mohammad taghi ghorbanian school of biology, damghan university, damghan,iran hadi hassanzadeh department of medical physics, semnan university of medical sciences, semnan, iran

since the uterine is a sensitive tissue to steroid hormones, the aim of the present study was to investigate the effects of 17β-estradiol (e2) and progesterone (p4) alone or in combination on morphological and morphometrically parameters of ovariectomized mouse uterus.adult virgin female mice (8-10 weeks old)were ovariectomized and treated with e2, p4, e2 followed by p4 and the oil vehicle alon...

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