TAKE HOME MESSAGES 1. Movement disorders involve the basal ganglia and associated structures, often affecting the globus pallidus (the output target of the striatum) 2. Abnormal involuntary movements are classified as hypokinetic or hyperkinetic, and are subclassified byspeed, duration and whether or not they are rhythmic. 3. Parkinsonism is characterized by the presence of at least 2 of the 4 ...

Sleep-related movement disorders should be differentiated from parasomnias, sleep-associated behavioral disorders, and epilepsy. Polysomnography (PSG) is the gold standard in evaluating such disorders. Periodic leg movement disorder during sleep (PLMS), hypnic jerks, bruxism, rhythmic movement disorder, restless legs syndrome, and nocturnal leg cramps have broadly been discu...

background: multiple sclerosis (ms) is an autoimmune inflammatory disease  that affects  the  central  nervous system. except tremor, other movement disorders such as parkinsonism are less frequent  in ms. however, some investigations  have shown inflammatory and autoimmune aspects of parkinson’s disease. in this study, we report eight new cases of ms who present parkinson’s disease. methods:  ...

background: restless and violent behaviors are common in emergency departments (eds), which need therapeutic interventions in most of the times. the first-generation anti-psychotic drugs are one of the most applicable therapeutic agents in the management of such patients, but their use has some limitations. some studies suggest midazolam as an alternative medicine. therefore, this study was per...

Neurons require long-distance microtubule-based transport systems to ferry vital cellular cargoes and signals between cell bodies and axonal or dendritic terminals. Considerable progress has been made on developing a molecular understanding of these processes and how they are integrated into normal neuronal functions. Recent work also suggests that these transport systems may fail early in the ...