Mixed Presence Groupware (MPG) is software that connects collocated and distributed collaborators together in a shared visual workspace. The problem is that collaborators in MPG focus their collaborative energies almost exclusively on their collocated partners, ignoring their distributed counterparts. This arises because remote collaborators are disembodied when compared to their collocated coh...

AIM To examine the expression of N-methylpurine-DNA glycosylase (MPG) gene and protein in glioma samples with different WHO grades and its association with patients' survival. METHODS Immunohistochemistry assay, quantitative real-time PCR and Western blot analysis were carried out to investigate the expression of MPG gene and protein in 128 glioma and 10 non-neoplastic brain tissues. RESULT...

Introduction The cellular membrane constitutes an effective barrier that protects the complex, yet highly ordered, intracellular compartment of the cell. Passage of molecules across this barrier is highly regulated and highly restricted, with molecular size and amphilicity being the most significant criteria. Cell penetrating peptides (CPPs) are a class of small cationic peptides that are able ...

Body DWI has been proposed recently as a sensitive tumour detection method. One of the major issues with abdominal DWI is signal loss in soft tissues. Recent study (1) showed that this is mainly due to cardiac pulsation. Voxel deformation due to cardiac motion combined with strong diffusion gradient pulse induces intra-voxel spin phase dispersion that causes signal loss in both left and right l...

When diffusion tensor was analyzed, increasing motion probing gradient (MPG) directions and increasing signal-to-noise ratio (SNR) as result might influence diffusion tensor calculation. This study determined that mean diffusivity (MD) and fractional anisotropy (FA) are calculated by changing MPG-directions or SNR in the volunteer. There were no statistically significant differences in MD, whic...

N-(2-Mercaptopropionyl)-glycine (MPG) is a synthetic aminothiol antioxidant that is used in the treatment of cystinuria, rheumatoid arthritis, liver and skin disorders. Recent studies have shown that MPG can function as a chelating, cardioprotecting and a radioprotecting agent. Several other studies have shown that it may also act as a free radical scavenger because of its thiol group. Thiol-co...

OBJECTIVE The A1C-Derived Average Glucose (ADAG) study demonstrated a linear relationship between HbA(1c) and mean plasma glucose (MPG). As glucose variability (GV) may contribute to glycation, we examined the association of several glucose variability indices and the MPG-HbA(1c) relationship. RESEARCH DESIGN AND METHODS Analyses included 268 patients with type 1 diabetes and 159 with type 2 ...

DNA repair is a major mechanism for minimizing mutations and reducing cancer risk. Here, we present the development of reproducible and specific enzymatic assays for methylpurine DNA glycosylase (MPG) repairing the oxidative lesions 1,N6-ethenoadenine (εA) and hypoxanthine (Hx) in peripheral blood mononuclear cells protein extracts. Association of these DNA repair activities with lung cancer wa...

OBJECTIVE This study examined the role of SNP rs2858056 of the MPG gene on the incidence and severity of rheumatoid arthritis (RA). METHODS This cohort study enrolled 365 RA patients and 375 age- and gender-matched healthy controls, all of whom had Han Chinese ethnicity and were from Taiwan. Gene polymorphism of the SNP rs2858056 of MPG was determined from genomic DNA. Allelic frequencies and...

MicroRNAs (miRNAs) are small non-coding RNAs that are important in the pathogenesis of multiple diseases and, therefore, may represent a novel class of targets for therapeutic intervention. However, like the majority of oligonucleotide-based strategies, there are obstacles to their clinical application, including poor cellular uptake due to the low permeability of the cell membrane to negativel...