The expression of mammary tumor virus (MTV) antigen in the milk and various organs of three non-inbred dd mouse stocks (ddO, ddN and ddY) was examined by the immunodiffusion (ID) and micro-immunodiffusion (micro-ID) tests. The rate of MTV antigen expression in the milk was 100% at the first lactation in ddO (6/6) and ddN mice (10/10), and 23% in ddY mice (3/13). Mammary tumor incidence was 13% ...

In the course of analyzing sites of proviral integration in tumors induced by mouse mammary tumor virus (MMTV), we have isolated recombinant DNA clones corresponding to the 5' and 3' ends of four endogenous MMTV proviruses present in BALB/c and BR6 mice. This has permitted the structural characterization of each locus by detailed restriction mapping and the preparation of DNA probes specific fo...

naTuRe medicine advance online publication Here, we describe a quantitative neuroimaging method to estimate the macromolecular tissue volume (MTV), a fundamental measure of brain anatomy. By making measurements over a range of field strengths and scan parameters, we tested the key assumptions and the robustness of the method. The measurements confirm that a consistent quantitative estimate of M...

T cells of mice display V beta-specific reactivity for a spectrum of mouse mammary tumor virus (Mtv) antigens; confrontation with these antigens during ontogeny causes substantial "holes" in the T cell repertoire. Since endogenous Mtv antigens are rare in other species, the question arises whether V beta-specific recognition of Mtv antigens is unique to mice. To examine this question, rat T cel...

This is an observational study to determine the most relevant parameter of ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for predicting recurrence in cervical cancer. Fifty-six patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIB-IVA cervical cancer who underwent pretreatment ¹⁸F-FDG PET/CT were enrolled. PET parameters in...

OBJECTIVE Metabolic activity and tumor burden are significant for prognosis and metastasis of non-small cell lung cancer (NSCLC), including maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG). Chemotherapy resistance is a great challenge for treating NSCLC patients and is also closely related with several biomarkers such as epidermal growt...

showed B particles on their surfaces in electron micrographs. On the basis of these and other studies, the authors suggested that B particles may be the only infectious form of MTV, occurring in both blood and mammary tissues. The present investigation was undertaken to determine whether MTV activity is inside or on the surface of the red blood cells and to test whether adsorption of B particle...

SUMMARY Neonatally thymectomized C3H MTV@ (mammary tumor vi rus) female mice which were grafted with syngeneic thymus from either MTV@ or MTV animals developed spontaneous mammary tumors as frequently as did sham-operated controls. Neonatally thymectomized C3H MTV@ females which were injected with spleen cells obtained from syngeneic MTV@ mice had a signfficant reduction in mammary tumor incide...

objective(s): this study aimed to evaluate the role of pretreatment suvmax and volumetric fdg positron emission tomography (pet) parameters in the differentiation between benign and malignant mediastinal tumors. in addition, we investigated whether pretreatment suvmax and volumetric fdg-pet parameters could distinguish thymomas from thymic carcinomas, and low-risk from high-risk thymomas.method...

Objective(s): This study aimed to evaluate the role of pretreatment SUVmax and volumetric FDG positron emission tomography (PET) parameters in the differentiation between benign and malignant mediastinal tumors. In addition, we investigated whether pretreatment SUVmax and volumetric FDG-PET parameters could distinguish thymomas from thymic carcinomas, and low-risk from high-risk thymomas.Method...