Normal male reproductive function, particularly ejaculation, requires the integrity of urogenital sensory input and its ascending spinal projections. After midthoracic chronic spinal cord injury, sexual dysfunction occurs in both rats and humans. Neurons in the medullary reticular formation (MRF) are involved in the processing of bilaterally convergent sensory inputs from multiple cutaneous, mu...

Cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL) due to Leishmania (V.) braziliensis are endemic in Paraguay. We performed a series of knowledge, attitudes, and practice (KAP) surveys simultaneously with individuals in endemic communities in San Pedro department (n = 463), health professionals (n = 25), and patients (n = 25). Results showed that communities were exposed to hig...

Clinicians involved in the diagnosis of mucocutaneous diseases should be aware that syphilis is still prevalent among humans and its accurate may require substantial clinical evaluation. Herein, we report a case primary presenting as an isolated ulcer on upper left labial oral mucosa. The lesion exhibited no specific features could have been easily mishandled. An important observation was prese...

The aim of this case report is to present a histologically diagnosed oral lichen planus excised by the CO2 laser. Oral lichen planus is a chronic inflammatory mucocutaneous disease of unknown etiology. Different treatments have been used to manage this condition. A 46 year-old female was referred to the Laser Clinic of the Dental School of the Federal University of Bahia to excise a lesion char...

RATIONALE Peutz-Jeghers syndrome (PJS) is an autosomal dominant genetic syndrome characterized by a unique type of gastrointestinal hamartomatous polyp associated with oral and anal mucocutaneous pigmentations. Peutz-Jeghers polyps occur most numerously in the small intestine but frequently in the colon and stomach, only a few cases have been reported in the duodenum. PATIENT CONCERN A furthe...

A 55 years old woman, was hospitalized in November 2011 for a Stevens-Johnson syndrome with severe mucosal impairment appeared three weeks after taking allopurinol (Zyloric®) for an hyperuricemia associated with arthralgia. She was put under symptomatic treatment after discontinuation of the offending molecule with a good mucocutaneous improvement. After healing of lesions of the oral mucosa in...

Leishmaniasis is an infectious disease that is endemic in tropical areas and in the Mediterranean. This condition spreads to 98 countries in four continents, surpassing 12 million infected individuals, with 350 million people at risk of infection. This disease is characterized by a wide spectrum of clinical syndromes, caused by protozoa of the genus Leishmania, with various animal reservoirs, s...

Lichen Planus (LP) is a chronic mucocutaneous disease with several variants defined by the configuration of lesions, the morphological appearance, and the site of involvement. Although exact cause of LP is not known, it is thought that it is most likely an immunologically mediated reaction especially a cell-mediated immune response of unknown origin. Typical lesion is seen as a pruritic, papula...

Mucocutaneous manifestations are common among patients on hemodialysis (HD). This study was undertaken to determine the prevalence of mucocutaneous manifestations in patients with end-stage renal disease (ESRD) who are on HD. In this cross-sectional, descriptive and analytic study conducted in 2009, 100 patients on HD at the Five Azar Hospital in Gorgan city were randomly selected. All the pati...