Cochlear implant devices are designed to provide sound sensation and improved speech understanding to people who are profoundly hearing impaired. Best speech recognition could be achieved by using multi-channel, multi-electrode cochlear implant devices. In a multichannel cochlear prosthesis, channel interaction and tissue damage are important issues to be solved. Speech processing and modidatio...

Methods This was a multi-centre inter-tester and intra-tester reliability study. Four podiatrists participated in this study, two public and two private practitioners. Three aspects of Doppler use were examined; the clinical Doppler technique, the evaluation of Doppler audio sounds and qualitative evaluation of Doppler waveforms. Participants meeting current guidelines for vascular screening at...

Increased phasic activity in the bladder smooth muscle of animal models and patients with detrusor overactivity has been suggested to underlie the pathophysiology of overactive bladder. Potassium (K+) channels are key regulators of bladder smooth muscle tone and thus may play a role in this altered phasic activity. In this study the effects of K+ channel modulators on the phasic activity of bla...

OBJECTIVESTo assess the usefulness of Tri-phasic computed tomography in evaluation hepatocellular carcinoma cirrhotic patients.METHODOLOGYThis cross-sectional study was carried out Radiology and Imaging Department Hayatabad Medical Complex Peshawar from October 2020 to September 2021 (01 year). CT done all patients. Patients with suspected diagnosed by clinical ultrasonography having high serum...

Here we show how anatomical and functional data recorded from patients undergoing stereo-EEG can be used to decompose the cortical processing following nerve stimulation in different stages characterized by specific topography and time course. Tibial, median and trigeminal nerves were stimulated in 96 patients, and the increase in gamma power was evaluated over 11878 cortical sites. All three n...

the aim of the present study was to investigate the effect of α2-adrenergic agonist (xylazine) andantagonist (yohimbine) on phasic pain during estrous cycle in female rats. adult female rats weighing 180-220 g were kept under controlled temperature (21-24°c) and light/dark conditions (light on at 6:00 a.m. and light off at 6:00 p.m.). animals were divided into four groups: 1) control group whic...

The efficacy of synaptic transmission varies greatly among synaptic contacts. We have explored the origins of differences between phasic and tonic crustacean neuromuscular junctions. Synaptic boutons of a phasic motor neuron release three orders of magnitude more quanta to a single action potential and show strong depression to a train, whereas tonic synapses are nearly unresponsive to single a...