نتایج جستجو برای: multidrug resistant mdr
تعداد نتایج: 204573 فیلتر نتایج به سال:
Multidrug-resistant tuberculosis (MDR-TB) and lately, extensively drug-resistant TB (XDR-TB) are increasing global health concerns. Here, we present the genome sequences of two MDR-TB isolates from Myanmar, one of 27 countries with a high MDR-TB burden, and describe a number of mutations consistent with these being XDR-TB isolates.
Clinical strains of Stenotrophomonas maltophilia are often highly resistant to multiple antibiotics, although the mechanisms of resistance are generally poorly understood. Multidrug resistant (MDR) strains were readily selected by plating a sensitive reference strain of the organism individually onto a variety of antibiotics, including tetracycline, chloramphenicol, ciprofloxacin, and norfloxac...
The emergence of multidrug-resistant (MDR) pathogens within biofilms in the cystic fibrosis lung results increased morbidity. An inhalation therapy derived from alginate, OligoG CF-5/20, is currently clinical trials for patients.
Drug-resistant Mycobacterium tuberculosis is challenging elimination of tuberculosis (TB). We evaluated risk factors for TB and levels of second-line drug resistance in M. tuberculosis in patients in Europe with multidrug-resistant (MDR) TB. A total of 380 patients with MDR TB and 376 patients with non-MDR TB were enrolled at 23 centers in 16 countries in Europe during 2010-2011. A total of 52....
The emergence of multidrug resistance among gram-negative bacilli is complex. Numerous factors need to be considered, including the biological fitness cost of resistance, fitnesscompensatory mutations and frequency and type of antibiotic exposure. A mathematical model evaluating these complex relationships was developed in an individual colonized with strains of pan-susceptible, single-, twoand...
Background Multidrug resistance (MDR) TB is on the rise globally and is associated with significant morbidity and mortality. Conventional culture based drug susceptibility testing (DST) for TB drugs is time consuming, leading to diagnostic delays contributing to higher TB morbidity and mortality and exacerbation of ongoing transmission. Moreover most of the NTM(Non tuberculous mycobacteria) tha...
multidrug-resistant (mdr) and extensively drug-resistant (xdr) tuberculosis (tb) are increasing globally. treatment options for these patients are very limited. although treatment of these patients with standardized regimen is associated with high mortality and morbidity, rational usage of new drugs might be promising. in this study we will review epidemiology of xdr-tb and tdr-tb in iran and t...
background and aim: in recent years, due to the indiscriminate and irrational use of synthetic drugs, the resistance of pathogenic microorganisms has increased; therefore, new compounds are vitally needed. the purpose of this study was to investigate the effect of ethanolic and aqueous extracts of berberis vulgaris on escherichia coli, klebsiella pneumoniae, proteus mirabilis, citrobacter frund...
Multidrug resistance (MDR) of human cancers is the major cause of failure of chemotherapy. To better understand the molecular events associated with the development of different types of MDR, two different multidrug-resistant gastric carcinoma cell lines, the MDR1/P-glycoprotein-expressing cell line EPG85-257RDB and the MDR1/P-glycoprotein-negative cell variant EPG85-257RNOV, as well as the cor...
We studied the epidemiology of drug-resistant tuberculosis (TB) in Vladimir Region, Russia, in 2012. Most cases of multidrug-resistant TB (MDR TB) were caused by transmission of drug-resistant strains, and >33% were in patients referred for testing after mass radiographic screening. Early diagnosis of drug resistance is essential for preventing transmission of MDR TB.
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