the simultaneous optimization of multiple responses is an important problem in the design of industrial processes in order to achieve improved quality. in this paper, we present a new metaheuristic approach including simulated annealing and particle swarm optimization to optimize all responses simultaneously. for the purpose of illustration and comparison, the proposed approach is applied to tw...

Aims: Probiotics are viable and useful microorganisms, which are beneficial factors for human and animal health by altering their microbial flora. Most of the probiotics belong to a large group of bacteria in the human gastrointestinal tract. There are several clinical shreds of evidence that show anti-carcinogenic effects of probiotics through altering digestive enzymes, inhibition of carcinog...