Chemical imaging aims to characterize the molecular patterns present in a tissue or surface. High-resolution images with high content of information represent clear advantage many research areas, such as biomedicine. Specific patterns, when related pathological traits, could help understanding events condition studied. composition different regions within may reveal interesting that cannot be d...

The boundaries of the set feasible bilinear solutions for three-component systems have been estimated in presence noise, as a sequel previous report on two-component data sets. Simulations involving significant degree overlap among component profiles both matrix modes analyzed using FACPACK and recently described sensor-wise N-BANDS model. latter computes upper lower envelopes showing maximum m...

Second order advantage of excitation-emission fluorescence matrix was applied for the simultaneous determination of ibuprofen and caffeine. The proposed method is based on the measurement of the native fluorescence and recording emission spectra of ibuprofen and caffeine in different excitation wavelengths. The mixture of these compounds was resolved by multivariate curve resolution coupled wit...

a new method was developed for the spectral resolution by further determination of three- and  four-component  mixtures  of  drugs in urine samples through  the complementary application of multivariate curve resolution-alternating least squares with correlation  constraint. in the current study, a simple method was proposed to construct a calibration set for the mixture of drugs in the presenc...