The steepest-descent method is a well-known and effective single-objective descent algorithm when the gradient of the objective function is known. Here, we propose a particular generalization of this method to multi-objective optimization by considering the concurrent minimization of n smooth criteria {J i } (i = 1,. .. , n). The novel algorithm is based on the following observation: consider a...

Hepatocellular carcinoma (HCC) ranks the sixth most common cancer and the third cause of cancer-related mortality worldwide. Recent studies identified that circ-ITCH Suppresses mutiple cancers proliferation via inhibiting the Wnt/beta-Catenin pathway. In current study, conducted a genetic association study together with epidemiological follow-up study to delineate the role of circ-ITCH in the d...

background: unwanted pregnancy not intended by at least one of the parents has undesirable consequences for the family and the society. in the present study, three classification models were used and compared to predict unwanted pregnancies in an urban population.   methods : in this cross-sectional study, 887 pregnant mothers referring to health centers in khorramabad, iran, in 2012 were selec...

caesarean section (c-section) rates have been increasing dramatically in the past decades around the world. this increase has been attributed to multiple factors such as maternal, socio-demographic and institutional fac-tors. therefore, this study examines the impact of maternal, socio-demographic and relevant characteristics on caesar-ean delivery in the northern region of bangladesh.this stud...

background: determining the mortality rate of diseases in a community is one of the main components in health care planning of that community. this study used a join point regression model to determine the trend of mortality due to diabetes mellitus (dm) in iran. materials and methods: the data on the rate of mortality due to dm were obtained from the reports of the iranian ministry of health. ...

in a finite stationary markov chain, transition probabilities may depend on some explanatoryvariables. a similar problem has been considered here. the corresponding posteriors are derived andinferences are done using these posteriors. finally, the procedure is illustrated with a real example.

smoking has become more prevalent in turkey than it has in those of western countries during the past decade. this study was conducted to make parameter estimations on gender related smoking habits with the minimum of variance. of the ninety-two researches related to smoking habits conducted from 1981 to 2003 in turkey, 60 were deemed appropriate for the application of meta analysis and meta re...