نتایج جستجو برای: mx1
تعداد نتایج: 518 فیلتر نتایج به سال:
در مطالعهی حاضر اثرات چای سبز (Camellia sinensis) بر روی بیان برخی ژنهای مرتبط با فعالیت ضد ویروسی شامل، IFN-γ، MX1، MX2، MX3 و HSP70 در ماهی قزلآلای رنگینکمان مورد بررسی قرار گرفت. 120 ماهی (با میانگین وزن 5/2±5/23 گرم) در چهار گروه با رژیمهای غذایی حاوی 0، 20، 100 و 500 میلیگرم در کیلوگرم خوراک چای سبز به مدت 35 روز تغذیه شدند. نتایج نشان داد چای سبز با مقدار 500 میلیگرم...
BACKGROUND Multiple sclerosis (MS) patients treated with interferon beta (IFNβ) are at risk of a declining response to treatment because of the production of IFNβ-neutralizing antibodies (NAbs). The expression of Myxovirus resistance protein A (MxA) mRNA is regarded as a marker of IFNβ bioactivity. AIMS The aim of this study was to analyze the kinetics of MxA mRNA expression during long-term ...
Mx proteins belong to the dynamin superfamily of high molecular weight GTPases and interfere with multiplication of a wide variety of viruses. Earlier studies show that nuclear mouse Mx1 and human MxA designed to be localized in the nucleus inhibit the transcription step of the influenza virus genome. Here we set a transient influenza virus transcription system using luciferase as a reporter ge...
Studying the interaction between proteins is key in understanding their function(s). A very powerful method that is frequently used to study interactions of proteins with other macromolecules in a complex sample is called co-immunoprecipitation. The described co-immunoprecipitation protocol allows to demonstrate and further investigate the interaction between the antiviral myxovirus resistance ...
Chronic fibrosing idiopathic interstitial pneumonia (IIP) can be divided into two main types: idiopathic pulmonary fibrosis (IPF), a steroid-resistant and progressive disease with a median survival of 2-3 years, and idiopathic non-specific interstitial pneumonia (INSIP), a steroid-sensitive and non-progressive autoimmune disease. Although the clinical courses of these two diseases differ, they ...
X nx1 system state matrix A nxn state transition matrix (possible time varying) Bnxm input matrix (possibly time varying) U mx1 input of system inputs Uideal mx1 matrix defining the input required to force perfect tracking. Xref nx1 matrix defining the path the states are to follow, periodic in time T. T The period of the repetitive motion: Xref(t)=Xref(t+T) W(t) Basis function for determining ...
The gene cluster for the biosynthesis of the heterocyclic quinone antibiotic saframycin Mx1 of Myxococcus xanthus DM504/15 was inactivated and tagged by Tn5 insertions. The tagged genes were cloned in Escherichia coli and used to select overlapping cosmid clones spanning 58 kb of the M. xanthus genome. Gene disruption experiments defined a > or = 18 kb contiguous DNA region involved in saframyc...
Abstract Human immunodeficiency virus (HIV) initiates a perpetual cycle of inflammation in the brain that results neuronal damage and consequent neurologic dysfunction. Since HIV preferentially infects damages specific regions, there is need for study antiviral immune markers region manner. We have evaluated expression (IFNa, IFNb, TRAIL, MX1) (CCL2, IL-6, IL-1b, IL-10) across nine regions our ...
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