نتایج جستجو برای: myasthenia gravis

تعداد نتایج: 7180  

Gholam ALi Yousefipour Mohammad Reza Haghshenas Nasrollah Erfani, Sara Yahyazadeh

Background: Myasthenia gravis (MG) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. The association of immunomodulator genes with different autoimmune disease has been studied in recent years. Objective: The aim of this study was to investigate correlation between a genetic variation in Stromal Ce...

2013
Anne Becker Nicole Ludwig Andreas Keller Björn Tackenberg Christian Eienbröker Wolfgang H. Oertel Klaus Fassbender Eckart Meese Klemens Ruprecht

BACKGROUND Myasthenia gravis is a disorder of neuromuscular transmission associated with autoantibodies against the nicotinic acetylcholine receptor. We have previously developed a customized protein macroarray comprising 1827 potential human autoantigens, which permitted to discriminate sera of patients with different cancers from sera of healthy controls, but has not yet been evaluated in ant...

Journal: :Journal of neurology, neurosurgery, and psychiatry 1997
N Sommer B Sigg A Melms M Weller K Schepelmann V Herzau J Dichgans

OBJECTIVE Ocular myasthenia gravis is a subtype of myasthenia gravis that causes relatively mild disability, but may convert into severe generalised muscle weakness. A universal management plan for ocular myasthenia gravis has not been established. This study was performed to determine the outcome of ocular myasthenia gravis with the currently available therapeutic options. METHODS Retrospect...

Journal: :Nursing standard (Royal College of Nursing (Great Britain) : 1987) 2017
Christopher Barber

Myasthenia gravis is a rare long-term neurological condition that is characterised by fluctuating skeletal muscle weakness and fatigue, as well as respiratory difficulties. It is both an acquired autoimmune disease and a chronic neuromuscular disorder. Because of its rarity, myasthenia gravis is relatively unknown and may be unfamiliar to many nurses. While there are various types of myasthenia...

Journal: :Postgraduate medical journal 1967
M N Prematilleke M Kumarasinhe C C Balasubramaniam

ROWLAND, L.P., HOEFER, P.F.A., ARANOW, H., JR. & MERRITr, H.H. (1956) Fatalities in myasthenia gravis. Neurology (Minneap.), 6, 307. SAHAY, B.M., BLENDIS, L.M. & GREENE, R. (1965) Relation between myasthenia gravis and thyroid disease. Brit. med. J. i, 762. SIMPSON, J.A. (1960) Myasthenia gravis: a new hypothesis. Scott. med. J. 5, 419. SIMPSON, J.A. (1964) Immunological disturbances in myasthe...

Journal: :Journal of rehabilitation medicine 2008
Che-Sheng Lin Juei-Hsiang Wang Yen-Ho Wang Shin-Liang Pan

Both myasthenia gravis and traumatic spinal cord injury are uncommon disorders and their concurrence is extremely rare. We report here the case of a man with stable myasthenia gravis with spinal cord injury due to a motor vehicle accident. His muscle strength and sensory function in all 4 limbs partially recovered during the initial hospitalization. However, after a later episode of pneumonia a...

Journal: :Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2007
M Raica Anca Maria Cîmpean Svetlana Encică T Scridon M Bârsan

There were investigated 15 cases with normal thymus removed during cardiac surgery and nine cases with clinical signs of myasthenia gravis. Four patients with myasthenia gravis had thymoma (three invasive, one non-invasive). Specimens were fixed in buffer formalin, embedded in paraffin and slides were stained with Hematoxylin-Eosin and Alcian blue-Safranin. Additional slides were stained for fa...

2016
Jun-Li Tsai Shang-Feng Tsai

BACKGROUND Myasthenia gravis superimposed with proteinuria is a very rare disorder with only 39 cases reported so far. Of these cases, the most commonly associated disorder is minimal change disease. Myasthenia gravis and minimal change disease are both related to the dysfunction of T lymphocytes and hence the 2 disorders may be connected. METHODS Here we report the first case on a patient di...

Journal: :Archives of neurology 2003
Mark J Kupersmith Robert Latkany Peter Homel

BACKGROUND Generalized myasthenia gravis will develop in more than 50% of patients who present with ocular myasthenia gravis, typically within 2 years. The optimal treatment of ocular myasthenia gravis, including the use of corticosteroids, remains controversial. In addition, the prevalence of thymoma and the optimal performance of the edrophonium chloride test for ocular myasthenia remain unkn...

Journal: :Virchows Archiv. B, Cell pathology including molecular pathology 1983
Hiroshi Onodera

Myasthenia gravis is an organ-specific autoimmune disease characterized by the production of anti-acetylcholine receptor antibodies. In this review, I describe the pathophysiological importance of the altered chemokine receptor-mediated signaling in the thymus and peripheral blood of myasthenia gravis patients. The epidemiological and clinical features of myasthenia gravis are also discussed.

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