Dear Editor, Mycosis fungoides is the most common type of cutaneous T cell lymphoma with a reported incidence of 0.5 cases per 100,000 people per year.1 The cause of mycosis fungoides is still unknown; however genetic and environmental factors have been implicated as possible pathologic factors.2 The disease might also be associated with human T cell lymphotropic virus type 1,3 which is endemic...

The association of mycosis fungoides and a primary cutaneous CD30+ lymphoproliferative disorder has been reported and probably represents different clinical aspects of a unique T-cell monoclonal expansion. In this study, 12 patients (6 men and 6 women) presented with lymphomatoid papulosis and mycosis fungoides. A TCRgamma gene rearrangement study was performed by an automated high-resolution P...

We tested the effect of2 exposure methods and 2 environmental factors, temperature and humidity, on Beauceria bassiana (Deuteromycotina: Hyphomycetes) mycosis in Hippodamia convergens Gut<;lin-Meneville (Coleoptera: Coccinellidae). We found that the standard EPA bioassay method of exposing nontarget insects by immersion resulted in a per-insect dose that was 5 times greater than that from spray...

INTRODUCTION Lymphomatoid papulosis is a chronic benign disease which may be associated with malignant lymphomas. This case illustrates the relapsing and remitting nature of both lymphomatoid papulosis and its potential of developing cutaneous T-cell lymphoma and narrow-band ultraviolet B (NB-UVB) phototherapy as a new modality of treatment of early-stage mycosis fungoides in these patients. ...

Background: Chemokines are a family of cytokines initially characterized by their capacity to induce chemotaxis, or directed leukocyte migrations. These receptors are activated by chemotactic cytokines called chemokines. Interactions between chemokines and chemokine receptors also are involved in tumorigenesis, migration and invasion of lymphoma cells.Methods: An English literature search...

A case of cerebral mycosis fungoides co-existing with progressive multifocal leucoencephalopathy presented with dementia. Brain biopsy established the diagnosis of mycosis fungoides after cerebrospinal fluid examinations and computerised tomographic scanning of the brain produced non-specific abnormalities.

This paper reviews the diagnostic and classificatory concepts of mycosis fungoides and Sézary syndrome in light of the latest normative publications. It describes the great variability of the clinical expression of mycosis fungoides in its early stages as well as the histopathological and immunohistochemical aspects that help with diagnosis. The diagnostic criteria required for characterizing S...

Mycosis fungoides is a low-grade cutaneous T-cell lymphoma. Early treatment often involves the use of topical chemotherapy such as mechlorethamine or carmustine although single-agent oral chemotherapy with alkylators is common for advanced disease. Recently, in a Phase I study of the new alkylating agent temozolomide, two mycosis fungoides patients experienced a complete response. The mechanism...

Guttural pouch mycosis is an emergency disease of the upper respiratory tract in equine species. In the present report a case of guttural pouch mycosis in a female, seven year-old pregnant donkey is described. A serious dyspnea which necessitated tracheotomy and preceding epistaxis was the most important clinical feature of guttural pouch mycosis in the donkey. A full and rapid effectiveness of...

It has recently been demonstrated that γδ T lymphocytes play a role in innate immunity to the neoplastic process; however, the significance of this subset of T lymphocytes in the pathophysiology of the most common form of cutaneous T cell lymphomas, mycosis fungoides, has yet to be investigated. In order to identify whether γδ T lymphocytes play a role in the progression of a pre-lymphomatous s...