Background & Aims: Myocardial infarction is one of the most common life threatening diseases in worldwide. Betaine is a safe and well tolerated compound that shows beneficial antioxidant and anti-inflammatory properties. Previous studies demonstrated, betaine reduce cardiovascular diseases but molecular mechanism of action did not known completely. Cathepsin G play pivotal role in tissue injury...

Ephedrine, metaraminol, epinephrine and maneuvers like carotid sinus stimulation used during intraoperative period have been postulated to cause temporary spasm of the coronary vessels leading decrease supply myocardium precipitating myocardial infraction in non-obstructive arteries (MINOCA). As an anaesthesiologists, we should be aware that even a dose as small 25 mcg infiltrated along with lo...

Compared with Type 1 diabetes, Type 2 diabetes (T2DM) does not affect the production of inhibit organs to absorb the produced insulin. Based on studies on the relationship between cardiac diseases and T2DM, the fact that many myocardial diseases including elevated risk for myocardial infraction, heart failure, and sudden cardiac death are common in T2DM. Therefore, studies in T2DM can benefic c...

BACKGROUND/AIM Pro-free radical oxidative stresses, as well as regulatory factors, are believed to be the key players in the development of diabetes and heart-related disorders such as myocardial infarction. The aim of the present study was to highlight the role of oxidative stress-responsive factors (reactive oxygen species [ROS], super oxide dismutase [SOD], and calpain-1) in type 2 diabetes ...