BACKGROUND The prevalence and clinical characteristics of psoriatic arthritis (PsA) in patients with psoriasis are not well described in Asian populations, including Koreans. OBJECTIVE The purpose of this study was to investigate the prevalence of PsA by using the classification of psoriatic arthritis (CASPAR) criteria on the basis of physical examination only, as well as its correlation with...

Background: Nail psoriasis affects approximately 50% of psoriasis patients and in many cases causes functional impairment in manual dexterity, pain and psychological stress. It is often overlooked, not treated effectively. Physicians often believe that the condition is difficult to treat. The risks of systemic conventional therapy are not justified and the difficulty of delivering effective top...

Psoriasis is the skin disease that most frequently affects the nails. Depending on the very nail structure involved, different clinical nail alterations can be observed. Irritation of the apical matrix results in psoriatic pits, mid-matrix involvement may cause leukonychia, whole matrix affection may lead to red lunulae or severe nail dystrophy, nail bed involvement may cause salmon spots, subu...

OBJECTIVE To evaluate the therapeutic efficacy of acitretin in patients with isolated nail psoriasis. DESIGN Open study involving 36 patients with moderate to severe nail psoriasis treated with acitretin. SETTING University-based outpatient dermatology clinic specializing in nail diseases. PATIENTS A total of 27 men and 9 women (mean age, 41 years) with nail psoriasis. INTERVENTION Ther...

BACKGROUND AND OBJECTIVES The nails are affected in a substantial number of patients with psoriasis. Nevertheless, few epidemiological studies have reported the characteristics of patients with nail psoriasis. Here we describe the epidemiology of nail psoriasis and the main characteristics of affected patients. PATIENTS AND METHODS We undertook a prospective case-control study at Hospital Uni...

The lifetime incidence of nail involvement in psoriatic patients is estimated to be 80-90%, and the nails can be affected in 10% to 55% of psoriatic patients. Psoriasis may also solely involve the nails, without any other skin findings, in which the treatment can be more challenging. Nail psoriasis may lead to considerable impairment in quality of life due to aesthetic concerns and more importa...

INTRODUCTION Nail involvement is common in psoriasis and has a considerable impact on patient quality of life. Its clinical presentation depends on which part of the nail is affected: the bed or the matrix. Fifty percent of patients report associated pain. In this study, we analyzed the safety and effectiveness of tazarotene 0.1% in a hydrophilic ointment in the treatment of nail psoriasis. M...

Nail changes are present in about 50% of psoriasis patients and tend to be refractory to conventional treatments. Pulsed dye laser has emerged as an alternative therapy. Our aim is to evaluate the efficacy of pulsed dye laser in nail psoriasis and the impact of treatment on quality of life. Fourteen patients were treated in monthly sessions for three months. The outcome assesment was made by th...

BACKGROUND Previous clinical trials have not evaluated improvement in nail psoriasis as a primary end point. OBJECTIVE This phase 3 trial evaluated the safety and efficacy of adalimumab in patients with moderate-to-severe fingernail psoriasis and moderate-to-severe plaque psoriasis. METHODS Patients were randomized 1:1 to 40 mg adalimumab every other week or placebo. The primary efficacy en...