Mucuna pruriens has been used by native Nigerians as a prophylactic for snakebite. The protective effects of M. pruriens seed extract (MPE) were investigated against the pharmacological actions of N. sputatrix (Javan spitting cobra) venom in rats. The results showed that MPE-pretreatment protected against cardiorespiratory and, to a lesser extent, neuromuscular depressant effects of N. sputatri...

The neutralizing capacity of antivenom prepared against Thai cobra (Naja kaouthia) venom was compared in mice using the homologous venom and that of spitting cobra (Naja siamensis). The amounts of antivenoms neutralizing a dose of 4 LD50 of the test venom were determined. Four antivenom preparations were used: three purified antivenoms and a crude antivenom, which were made using N. kaouthia ve...

New records are given of water mites from Vogelkop, New Guinea. A total of 33 species is recorded, including the descriptions of a representative of a new genus, i.e. Dropursides aberratus, and of twelve further species new to science, i.e. Hydrobaumia purpurea, Oxus manokwariensis, Limnesia multiscutata, Limnesia vogelkop, Australiobates elongatus, Unionicola novaeguineae, Neumania silvestris,...

The venoms from central Asian snakes (Echis carinatus, Echis multisquamatus, Vipera ursini, Vipera lebetina, Agkistrodon halys halys and Naja naja oxiana) contain several enzymes with amidolytic- and procoagulant activity. We have characterized the activities and the mol. wts of the venom enzymes that are able to convert a number of commercially available chromogenic substrates for activated co...

Snake venoms contain a rich variety of factors which affect blood coagulation. There have been few reports on the anticoagulant activity of the venom of different cobras, but no such observations have been made on the Iranian cobra, although a procoagulant factor has been described. In this study an anticoagulant factor has been purified from the venom of Naja naja oxiana using gel filtrat...

3.10. Respirations 7? per minute. 3.13. Respirations 7 per minute. 3.15. About "01 grain of dried cobra-poison dissolved in ? cub. centim. of water was injected into the vein of dog's leg. Immediately the animal became very restless, and tried in vain to vomit. Respirations 7 per minute. 3.21. Constant retching, but no vomiting. Respirations 7. 3.23. About 02 grain more was injected. 3 27. Cons...

Conventional treatment of Naja naja oxiana (NNO) envenoming requires large volumes of equine antivenin raised against NNO crude venom. The poor efficiency of this antivenin is assumed to be due to the high molecular weight non-toxic proteins, a strong immunogen, present in the crude venom. These proteins cause depression of antibody formation against the low molecular weight toxic components of...

snake venoms contain a rich variety of factors which affect blood coagulation. there have been few reports on the anticoagulant activity of the venom of different cobras, but no such observations have been made on the iranian cobra, although a procoagulant factor has been described. in this study an anticoagulant factor has been purified from the venom of naja naja oxiana using gel filtration f...