0

The unique structural features and stealth properties of a recently developed red blood cell membrane-cloaked nanoparticle (RBC-NP) platform raise curiosity over the interfacial interactions between natural cellular membranes and polymeric nanoparticle substrates. Herein, several interfacial aspects of the RBC-NPs are examined, including completeness of membrane coverage, membrane sidedness upo...

Treatment of malignant gliomas represents one of the most formidable challenges in oncology. The combination of surgery, radiation, and chemotherapy yields median survivals of less than one year. Here we demonstrate the use of a minimally invasive surgical technique, convection-enhanced delivery (CED), for local administration of a novel nanoparticle liposome containing topotecan. CED of this l...

In cooperative games, a key question is to find a division of payoffs to coalition members in a fair manner. Nucleolus is one of such solution concepts that provides a stable solution for the grand coalition. We study the computation of the nucleolus of a number of cooperative games, including fractional matching games and fractional edge cover games on general weighted graphs, as well as verte...

Motivated by the need for succinct representations of all “small” transversals (or hitting sets) of a hypergraph of fixed rank, we study the complexity of computing such a representation. Next, the existence of a minimal hitting set of at least a given size arises as a subproblem. We give one algorithm for hypergraphs of any fixed rank, and we largely improve an earlier algorithm (by H. Fernau,...

Article history: Received 21 October 2013 Received in revised form 30 September 2014 Accepted 21 October 2014 Available online 28 October 2014 Communicated by G. Ausiello

With the remarkable progress of non-invasive molecular imaging techniques, the nanotechnology could provide powerful tools for development of diagnostic and therapeutic agents in bio-and nano-medicine field. Several imaging techniques including PET and MRI system have been developed for diagnosis, providing functional and anatomical information. Recently, the combined system of PET/MRI imaging ...

Dilution of contact, hard sphere-like, nanoparticle-nanoparticle interactions upon mixing plays a key role in explaining nanoparticle dispersion in athermal all-polymer nanocomposites, as illustrated for polystyrene-nanoparticle/linear-polystyrene blends as a model system.