Attempts to improve drug delivery from conventional jet nebulizers have included the use of storage systems to reduce drug wastage during exhalation. Venturi nebulizers enhance drug delivery during inhalation, reducing treatment times and drug wastage. This study investigated the effect of age on inhaled dose from a conventional jet nebulizer (Acorn) used both with and without a storage chamber...

BACKGROUND: Continuous nebulization has become popular for treating patients with severe reversible airway disease. Continuous nebulization therapy has been shown to be safe, effective, and labor efficient as compared to other traditional medication aerosol treatments 1-11 . Although numerous studies have been done evaluating the clinically efficacy of continuous nebulization, little work has b...

The AeroEclipse® BAN (Trudell Medical International (TMI), London, Canada) was initially developed for use in the hospital environment, optimized for medication delivery using air or oxygen supplied at 50 psig pressure (2, 3). This article describes initial laboratory data with a version (AeroEclipse-XL®) optimized for operation by either table-top (OmbraTM table-top compressor, TMI, 230V AC ve...

background: complications of ventolin as the most common drug used for bronchiolitis are widely known. the present study was conducted to determine the efficacy of hypertonic saline 3%, compared with ventolin, for treatment of acute bronchiolitis in children.   methods : this double-blinded clinical trial study was conducted in hajar hospital, shahrekord, iran, from 2011 to 2012. a total of 70 ...

The present study was undertaken to determine if beta-agonists delivered by nebulizer provide better clinical responses than MDI therapy in status asthmaticus. We divided 28 hospitalized asthmatic patients into three groups. Group 1 received albuterol by MDI with InspirEase. Group 2 received nebulized albuterol. Group 3 received nebulized metaproterenol. Both nebulizer regimens resulted in sign...

Tavana S1, Nadi E1, Ansari M2, zeraati F3, Hashemi H1, Mani Kashani Kh4, Mavallat M5 1. Assistant professor, Department of internal, Faculty of medicine, Hamedan University of medical sciences 2. Associate professor, Department of internal, Faculty of medicine, Hamedan University of medical sciences 3. Associate professor, Department of Pharmacology, Faculty of medicine, Hamedan Univers...

BACKGROUND Aerosol and humidification therapy are used in long-term airway management of critically ill patients with a tracheostomy. The purpose of this study was to determine delivery efficiency of jet and mesh nebulizers combined with different humidification systems in a model of a spontaneously breathing tracheotomized adult with or without exhaled heated humidity. METHODS An in vitro mo...

BACKGROUND Nebulized drug delivery is a cornerstone of therapy for obstructive lung disease, but the ideal nebulizer design is uncertain. The breath-actuated nebulizer (BAN) may be superior to conventional nebulizers. This study compared the BAN to standard nebulizer with regard to efficacy, safety, and patient and respiratory therapist (RT) satisfaction. METHODS Adults admitted to the hospi...

BACKGROUND Jet nebulizers constitute the aerosolization devices most frequently used during mechanical ventilation. Continuous nebulization can influence the delivered tidal volume (V(T)) and lead to significant medication loss during expiration. Ventilators thus provide integrated jet nebulization systems that are synchronized during inspiration and ostensibly keep VT constant. METHODS This ...

BACKGROUND Noninvasive ventilation (NIV) is usually applied using bi-level positive airway pressure devices, and many of these devices use a single-limb patient circuit with an integrated leak port to purge the circuit of exhaled carbon dioxide. Sometimes bronchodilator therapy is indicated in pediatric patients, but there have been no studies of the optimal nebulizer position, with respect to ...