The granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN). The antinuclear (ANA) and...

how to cite this article: salehi omran mr, nooreddini h, baghdadi f. acute necrotizing encephalopathy of childhood; a case report. iran j child neurol. 2013 spring;7(2):51-54.   abstract acute necrotizing encephalopathy of childhood (anec) is an atypical disease followed by respiratory or gastrointestinal infection, high fever, which is accompanied with rapid alteration of consciousness and sei...

Necrotizing fasciitis is a rapidly progressive infectious disease of the soft tissue with high mortality and morbidity rates. Necrotizing fasciitis is occasionally located in the head and neck region and develops after odontogenic infections. Factors affecting treatment success rates are early diagnosis, appropriate antibiotic treatment, and surgical debridement. We present a necrotizing fascii...

BACKGROUND Patent ductus arteriosus is a risk factor for the development of necrotizing enterocolitis. The use of indomethacin to treat patent ductus arteriosus in preterm infants may either decrease the incidence of necrotizing enterocolitis by stabilizing or closing the ductus arteriosus or increase its incidence by a direct constricting effect on mesenteric blood vessels. The authors sought ...

Background: Necrotizing enterocolitis is one of the serious complications of prematurity. Eosinophilia has not been proposed as a classical laboratory abnormality in NEC. Previous studies suggest that eosinophilia during NEC may be a sign of allergic enterocolitis. Case presentation: We present a premature neonate with birth weight of 1280 grams with abdominal distention, bilious gastric resid...

Necrotizing fasciitis is known to be a highly lethal infection of deep-seated subcutaneous tissue and superficial fascia. Reports of necrotizing fasciitis due to Streptococcus pneumoniae are exceedingly rare. We report a case of necrotizing fasciitis in a 62-yr-old man with liver cirrhosis and diabetes mellitus. He presented with painful swelling of left leg and right hand. On the day of admiss...

Introduction: Necrotizing sialometaplasia is a rare, benign, and self-limiting inflammatory lesion that commonly involves minor salivary glands. It is theoretically associated with ischemia. It is commonly found in the palate, and laryngeal presentation is a very unusual entity. Almost half of such cases have an underlying malignancy; therefore, suspicion of a malignant lesion should be high wh...

Necrotizing fasciitis of the head and neck is a rare but rapidly progressive infection involving the skin, subcutaneous tissue, and fascia. We report 4 cases of cervicofacial necrotizing fasciitis with similar patterns of presentation. All the 4 cases presented with an odontogenic source and no underlying medical condition. All the patients had tooth extraction and serial wound debridement. Thr...

background probiotics are thought to interfere with the mechanisms involving in the pathogenesis of necrotizing enterocolitis in neonates. objectives this study was planned to assess the effect of prophylactic probiotics for the prevention of necrotizing enterocolitis in low birth weight neonates. patients and methods this prospective triple-blinded, interventional, randomized clinical trial en...

Few studies have analyzed necrotizing fasciitis in children, and all have relied on cases of necrotizing fasciitis in the abdomen, head, and neck region. The authors sought to correlate the preoperative values of several laboratory tests previously validated in the adult literature, such as the Laboratory Risk Indicator for Necrotizing Fasciitis, with surgically confirmed necrotizing fasciitis ...